Rhodamine Analogues for Molecular Ruler Applications
This work was supported by the National Institute on Deafness and Other Communication Disorders at the National Institutes of Health (R21 DC010231; R01 DC012588).
Dyes and Pigments
A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally.
Locate the Document
Yu-Hsuan Chu, Jorge O. Escobedo, Meiyan Jiang, Peter S. Steyger, Robert M. Strongin. (2016). Rhodamine analogs for molecular ruler applications, Dyes and Pigments, Volume 126, Pages 46-53.