Table S2. Predicted age of regulatory proteins,,
Protein,Gain node*,Age
STM3098,11,young
HutC,11,young
HpaR,11,young
YefM,14,young
STM3533,14,young
STM3516,15,young
STM2738,18,young
EbgR,25,young
PrlF,25,young
HipB,25,young
HipA,25,young
MhpR,25,young
HcaR,25,young
YafO,25,young
QuuD,25,young
YedW,26,young
MqsR,27,young
YafQ,27,young
HicA,28,young
YefM,29,young
YoeB,29,young
PaaX,29,young
YjhI,48,young
RnlA,48,young
YagI,48,young
TorI,48,young
STM2239,taxa-specific (GCF_000210855.2),young
MntR,6,middle
SrlR,6,middle
NemR,6,middle
BluR,6,middle
SutR,6,middle
YcdC,6,middle
Nac,6,middle
Ada,7,middle
FrmR,7,middle
MarA,7,middle
EnvR,7,middle
CecR,7,middle
NarL,7,middle
MarR,7,middle
AidB,7,middle
TreR,7,middle
CsgD,7,middle
YqjI,7,middle
YdcI,7,middle
YgaV,7,middle
MalI,7,middle
ChbR,8,middle
RcnR,8,middle
McbR,8,middle
UlaR,8,middle
YiaJ,8,middle
MngR,8,middle
BetI,8,middle
NikR,9,middle
DmlR,9,middle
PrpR,9,middle
YgiV,9,middle
AllR,9,middle
YfaX,9,middle
UidR,9,middle
MazF,9,middle
MurR,9,middle
AlaS,1,old
RpsG,1,old
TyrR,1,old
Hns,1,old
LexA,1,old
NrdR,1,old
HdfR,1,old
ArgR,1,old
Efp,1,old
Fis,1,old
Hfq,1,old
RplJ,1,old
RplA,1,old
RplT,1,old
RpsD,1,old
ThrS,1,old
ArgP,1,old
FadR,1,old
PhoU,1,old
ArcA,1,old
AccD,1,old
RplM,1,old
OmpR,1,old
Zur,1,old
AsnC,1,old
Lrp,1,old
Crp,1,old
GlpR,1,old
PdhR,1,old
CytR,1,old
GntR,1,old
PurR,1,old
RpiR,1,old
FabR,1,old
CpxR,1,old
MtlR,1,old
RraB,1,old
RpsA,1,old
Rnr,1,old
Hpf,1,old
SgrR,1,old
LrhA,1,old
PspF,1,old
LipB,1,old
RplD,1,old
RppH,1,old
RplY,1,old
CsrA,1,old
ComR,1,old
NimR,1,old
PgrR,1,old
Pnp,1,old
YfjG,1,old
YfiA,1,old
Fur,1,old
YbeB,1,old
YjjK,1,old
Rne,1,old
Csp,1,old
PutA,2,old
SlyA,2,old
DeoR,2,old
MprA,2,old
AcrR,2,old
RcsB,2,old
IclR,2,old
NadR,2,old
FlgM,2,old
PtsJ,2,old
NsrR,2,old
MraZ,2,old
CpxP,3,old
KdgR,3,old
ExuR,3,old
AraC,5,old
LacI,5,old
AscG,5,old
Rmf,Undetermined,Undetermined
RelE,Undetermined,Undetermined
RelB,Undetermined,Undetermined
BdcR,Undetermined,Undetermined
SymE,Undetermined,Undetermined
HigB,Undetermined,Undetermined
DinJ,Undetermined,Undetermined
,,
* Node numbers as shown in Figure S1,,