PDB,Mutation,solubility change,Hydrophobicity change for each residue,Average Hydrophobicity change for multi-point mutant
1BIZ A,1 185 ASN,Decreased,1 185 ASN(4.429), 
1BIZ A,1 185 ASP,Decreased,1 185 ASP(3.714), 
1BIZ A,1 185 ILE,Decreased,1 185 ILE(13.143), 
1BIZ A,1 185 LEU,Decreased,1 185 LEU(12.143), 
1BIZ A,1 185 PHE,Decreased,1 185 PHE(13.143), 
1BIZ A,1 185 VAL,Decreased,1 185 VAL(12.429), 
1CI5 A,6 21 VAL 85 THR 1 PHE 9 VAL 58 VAL 93 LEU,Decreased,6 21 VAL(8.714) 85 THR(1.429) 1 PHE(8) 9 VAL(12.429) 58 VAL(12.429) 93 LEU(4.857),7.976333333
1COL A,1 140 CYS,Decreased,1 140 CYS(2.143), 
1COL A,1 140 LYS,Decreased,1 140 LYS(-12.143), 
1COL A,1 140 PHE,Decreased,1 140 PHE(1),
1COL A,2 130 PHE 140 PHE,Decreased,2 130 PHE(1) 140 PHE(1),1
1COL A,2 86 PHE 140 PHE,Decreased,2 86 PHE(1) 140 PHE(1),1
1COL A,3 86 PHE 130 PHE 140 PHE,Decreased,3 86 PHE(1) 130 PHE(1) 140 PHE(1),1
1FGA A,1 26 SER,Decreased,1 26 SER(5.143),
1FGA A,1 70 SER,Decreased,1 70 SER(-2.857),
1FGA A,1 93 SER,Decreased,1 93 SER(-8),
1JW4 A,1 232 GLU,Decreased,1 232 GLU(-8.429),
1JW4 A,1 242 GLU,Decreased,1 242 GLU(-5.143),
1JW4 A,1 317 GLU,Decreased,1 317 GLU(-9.429),
1JW4 A,2 32 ASP 33 PRO,Decreased,2 32 ASP(-12.28) 33 PRO(-12.28),-12.28
1MSC A,1 104 VAL,Decreased,1 104 VAL(-0.714),
1MSC A,1 107 THR,Decreased,1 107 THR(-1.429),
1MSC A,1 109 LEU,Decreased,1 109 LEU(8.429),
1MSC A,1 27 SER,Decreased,1 27 SER(0.714),
1MSC A,2 26 THR 118 PHE,Decreased,2 26 THR(-1.429) 118 PHE(0),-0.7145
1MSC A,2 48 ALA 109 HIS,Decreased,2 48 ALA(-4.429) 109 HIS(-3.713),-4.071
1MSC A,3 4 SER 32 ARG 50 ARG,Decreased,3 4 SER(-8) 32 ARG(-7.714) 50 ARG(0.714),-5
1MSC A,4 24 SER 46 ARG 96 VAL 116 SER,Decreased,4 24 SER(0.714) 46 ARG(-9.857) 96 VAL(4.429) 116 SER(0.714),-1
1MSC A,4 61 GLU 103 PHE 106 ARG 129 HIS,Decreased,4 61 GLU(3.714) 103 PHE(5.429) 106 ARG(5.429) 129 HIS(0.714),3.8215
1MSC A,5 21 SER 24 ASP 40 ARG 46 TYR 79 ALA,Decreased,5 21 SER(-3.571) 24 ASP(-3.571) 40 ARG(0.714) 46 TYR(-5.429) 79 ALA(-4.429),-3.2572
1MSC A,5 6 LEU 12 ASP 33 THR 56 CYS 95 LEU,Decreased,5 6 LEU(8.429) 12 ASP(-0.714) 33 THR(-6.571) 56 CYS(9.857) 95 LEU(-1) ,2.0002
1MSC A,7 12 ASP 34 GLY 52 PRO 92 MET 101 ARG 109 LEU 120 THR,Decreased,7 12 ASP(0.286) 34 GLY(-2.143) 52 PRO(0.714) 92 MET(1) 101 ARG(9.857) 109 LEU(-8.426) 120 THR(-2.633),-0.192142857
1MSC A,9 15 ASN 24 SER 29 ALA 32 CYS 45 SER 60 THR 98 TYR 104 ASN 126 PRO,Decreased,9 15 ASN(2.571) 24 SER(-1.143) 29 ALA(2.286) 32 CYS(2.286) 45 SER(1.429) 60 THR(6.571) 98 TYR(-4.857) 104 ASN(-0.980) 126 PRO(0.714),0.986333333
1NZX A,1 19 TYR,Decreased,1 19 TYR(-5.429),
1RGG A,1 76 ARG,Decreased,1 76 ARG(-2.143),
1RGG A,1 76 ASN,Decreased,1 76 ASN(-2.143),
1RGG A,1 76 LEU,Decreased,1 76 LEU(5.571),
1RGG A,1 76 LYS,Decreased,1 76 LYS(-6.571),
1RGG A,1 76 PHE,Decreased,1 76 PHE(6.571),
1RGG A,1 76 PRO,Decreased,1 76 PRO(-2.143),
1RGG A,1 76 TRP,Decreased,1 76 TRP(5.571),
1RGG A,1 76 VAL,Decreased,1 76 VAL(5.857),
1WUU A,1 198 VAL,Decreased,1 198 VAL(4.429),
1WUU A,1 28 LYS,Decreased,1 28 LYS(-4.429),
1WUU A,1 28 THR,Decreased,1 28 THR(2.143),
1WUU A,1 288 MET,Decreased,1 288 MET(7.714),
1WUU A,1 32 MET,Decreased,1 32 MET(-0.286),
1WUU A,1 346 SER,Decreased,1 346 SER(-2.143),
1WUU A,1 349 SER,Decreased,1 349 SER(-2.143),
1WUU A,1 36 ARG,Decreased,1 36 ARG(-2.857),
1WUU A,1 384 PRO,Decreased,1 384 PRO(-3.571),
1WUU A,1 44 TYR,Decreased,1 44 TYR(-0.714),
1WUU A,1 68 CYS,Decreased,1 68 CYS(9.857),
1YUE A,2 89 ALA 90 ALA,Decreased,2 89 ALA (4.286) 90 ALA(4.286),4.286
1Z0Q A,1 19 MET,Decreased,1 19 MET(-1),
1Z0Q A,1 32 SER,Decreased,1 32 SER(-8),
2D60 B,1 6 PHE,Decreased,1 6 PHE(9.429),
2D68 A,1 104 MET,Decreased,1 104 MET(0),
2D68 A,1 127 MET,Decreased,1 127 MET(0),
2D68 A,1 63 MET,Decreased,1 63 MET(12.143),
2D68 A,1 69 MET,Decreased,1 69 MET(12.143),
2D68 A,1 74 PHE,Decreased,1 74 PHE(0.714),
2D68 A,1 87 MET,Decreased,1 87 MET(0),
2D68 A,1 90 ALA,Decreased,1 90 ALA(1.429),
2D68 A,1 97 ALA,Decreased,1 97 ALA(4.286),
2D68 A,2 90 ALA 97 ALA,Decreased,2 90 ALA (1.429)97 ALA (4.286),2.8575
3IQS A,1 260 ALA,Decreased,1 260 ALA(-4.143),
3IQS A,1 261 ALA,Decreased,1 261 ALA(-6.286),
3IQS A,1 269 ALA,Decreased,1 269 ALA(-4.143),
3IQS A,1 281 ALA,Decreased,1 281 ALA(-6.286),
3IQS A,1 288 ALA,Decreased,1 288 ALA(-6.286),
3IQS A,1 308 ALA,Decreased,1 308 ALA(-6.286),
8API A,1 358 LEU,Decreased,1 358 LEU(0),
8API A,2 345 LEU 358 ARG,Decreased,2 345 LEU(5.571) 358 ARG(-7.714),-1.0715
9ILB A,1 10 ASN,Decreased,1 10 ASN(-7.714),
9ILB A,1 10 ASP,Decreased,1 10 ASP(-8.429),
9ILB A,1 97 ARG,Decreased,1 97 ARG(4.429),
9ILB A,1 97 VAL,Decreased,1 97 VAL(12.429),
1BIZ A,1 131 ALA,Increased,1 131 ALA(-4.143),
1BIZ A,1 165 LYS,Increased,1 165 LYS(-12.429),
1COL A,1 140 LEU,Increased,1 140 LEU(0),
1COL A,2 113 PHE 140 CYS,Increased,2 113 PHE(13.143) 140 CYS(2.143),7.643
1COL A,2 113 PHE 140 LEU,Increased,2 113 PHE(13.143) 140 LEU(0),6.5715
1COL A,2 113 PHE 140 LYS,Increased,2 113 PHE(13.143) 140 LYS(-12.143),0.5
1J3I A,1 27 GLU,Increased,1 27 GLU(3.714),
1J3I A,2 35 GLN 37 ARG,Increased,2 35 GLN(-13.857) 37 ARG(-13.857),-13.857
1J3I A,2 35 GLY 37 LEU,Increased,2 35 GLY(-2.571) 37 LEU(-2.571),-2.571
1J3I A,2 35 LEU 37 ARG,Increased,2 35 LEU(-5.429) 37 ARG(-5.429),-5.429
1J3I A,2 35 LEU 37 THR,Increased,2 35 LEU(-3.286) 37 THR(-3.286),-3.286
1LVM A, 3 17 SER 68 ASP 77 VAL,Increased,2 17 SER(-6.571)  80 SER(0.714),-2.9285
1LVM A,2 17 SER  80 SER,Increased,3 17 SER(-1.429) 68 ASP(-0.714) 77 VAL(-0.714),-0.952333333
1NZX A,1 104 THR,Increased,1 104 THR(-1.429),
1NZX A,1 203 HIS,Increased,1 203 HIS(0.714),
1RGG A,1 76 ALA,Increased,1 76 ALA(1.429),
1RGG A,1 76 ASP,Increased,1 76 ASP(-2.857),
1RGG A,1 76 CYS,Increased,1 76 CYS(7.714),
1RGG A,1 76 GLU,Increased,1 76 GLU(-2.857),
1RGG A,1 76 GLY,Increased,1 76 GLY(0.714),
1RGG A,1 76 HIS,Increased,1 76 HIS(3),
1RGG A,1 76 ILE,Increased,1 76 ILE(6.571),
1RGG A,1 76 MET,Increased,1 76 MET(5.571),
1RGG A,1 76 SER,Increased,1 76 SER(-1.429),
1Z0Q A,1 19 ALA,Increased,1 19 ALA(-5.143),
1Z0Q A,1 19 ARG,Increased,1 19 ARG(-8.714),
1Z0Q A,1 19 ASN,Increased,1 19 ASN(-8.714),
1Z0Q A,1 19 ASP,Increased,1 19 ASP(-9.429),
1Z0Q A,1 19 CYS,Increased,1 19 CYS(1.143),
1Z0Q A,1 19 GLN,Increased,1 19 GLN(-9.429),
1Z0Q A,1 19 GLU,Increased,1 19 GLU(-9.429),
1Z0Q A,1 19 GLY,Increased,1 19 GLY(-5.857),
1Z0Q A,1 19 HIS,Increased,1 19 HIS(-3.571),
1Z0Q A,1 19 ILE,Increased,1 19 ILE(0),
1Z0Q A,1 19 LEU,Increased,1 19 LEU(-1),
1Z0Q A,1 19 LYS,Increased,1 19 LYS(-13.143),
1Z0Q A,1 19 PRO,Increased,1 19 PRO(-8.714),
1Z0Q A,1 19 SER,Increased,1 19 SER(-8),
1Z0Q A,1 19 THR,Increased,1 19 THR(-6.571),
1Z0Q A,1 19 TRP,Increased,1 19 TRP(-1),
1Z0Q A,1 19 TYR,Increased,1 19 TYR(-4.286),
1Z0Q A,1 19 VAL,Increased,1 19 VAL(-0.714),
1Z0Q A,1 34 PRO,Increased,1 34 PRO(-8.714),
1Z0Q A,2 19 SER 34 PRO,Increased,2 19 SER(-8) 34 PRO(-7.714),-7.857
1Z0Q A,3 12 ALA 32 THR 34 PRO,Increased,3 12 ALA(-4.429)32 THR(-14.285) 34 PRO(-14.285),-10.99966667
1Z0Q A,4 12 GLU 18 GLU 35 THR 41 ASN,Increased,4 12 GLU(-8.714) 18 GLU(-8.174) 35 THR(-5.571) 41 ASN(-8.714),-7.92825
1Z0Q A,4 4 ILE 8 PRO 24 ALA 34 PRO,Increased,4 4 ILE(0) 8 PRO(-0.714) 24 ALA(-4.429) 34 PRO(-7.714),-3.21425
1Z0Q A,5 6 GLN 12 ALA 24 ALA 32 MET 36 GLY,Increased,5 6 GLN(-5.857) 12 ALA(-4.429) 24 ALA(3.571) 32 MET(-1)  36 GLY(-5.143),-2.5716
2BND A,1 159 ASP,Increased,1 159 ASP(-0.714),
2D60 B,1 6 LEU,Increased,1 6 LEU(8.429),
2D60 B,1 6 TRP,Increased,1 6 TRP(8.429),
3IQS A,1 234 ALA,Increased,1 234 ALA(-4.143),
3IQS A,1 235 ALA,Increased,1 235 ALA(-4.143),
3IQS A,1 241 ALA,Increased,1 241 ALA(-5.143),
3IQS A,1 253 ALA,Increased,1 253 ALA(-4.143),
3IQS A,1 371 ALA,Increased,1 371 ALA(-4.143),
8API A,2 351 GLU 358 ARG,Increased,2 351 GLU(-8.429) 358 ARG(-7.714),-8.0715
9ILB A,1 10 THR,Increased,1 10 THR(-5.571),
9ILB A,1 97 GLY,Increased,1 97 GLY(7.286),
,,, ,