The authors thank the National Institutes of Health for continued support of the efforts in creating functional molecular probes via grant RO1 EB2044.
Fluorescent dyes -- Applications to bioimaging, Fluorescein, Fluorescent probes, Infrared spectroscopy
Fluorescent dyes based on small organic molecules that function in the near infra red (NIR) region are of great current interest in chemical biology. They allow for imaging with minimal autofluorescence from biological samples, reduced light scattering and high tissue penetration. Herein, examples of ongoing NIR fluorophore design strategies as well as their properties and anticipated applications relevant to the bioimaging are presented.
Escobedo, Jorge O.; Rusin, Oleksandr; Lim, Soojin; and Strongin, Robert M., "NIR Dyes for Bioimaging Applications" (2010). Chemistry Faculty Publications and Presentations. 56.