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Fluorescent dyes -- Applications to bioimaging, Fluorescein, Fluorescent probes, Infrared spectroscopy


Fluorescent dyes based on small organic molecules that function in the near infra red (NIR) region are of great current interest in chemical biology. They allow for imaging with minimal autofluorescence from biological samples, reduced light scattering and high tissue penetration. Herein, examples of ongoing NIR fluorophore design strategies as well as their properties and anticipated applications relevant to the bioimaging are presented.


NOTICE: this is the author’s version of a work that was accepted for publication in Current Opinion In Chemical Biology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Current Opinion In Chemical Biology, 14(1), 64-70 and can be found online at:

This manuscript version is made available under the CC-BY-NC-ND 4.0 license



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