First Advisor

Brooke Napier

Date of Award

Spring 6-16-2022

Document Type

Thesis

Degree Name

Bachelor of Science (B.S.) in Biology and University Honors

Department

Biology

Language

English

Subjects

Gastrointestinal system -- Microbiology, Metabolism -- Disorders, Sleep disorders, Comorbidity

DOI

10.15760/honors.1202

Abstract

The crosstalk between the gut microbiome and sleep affects many aspects of human health. This paper looks at metabolic disorders affected by sleep deprivation, sleep disorders affected by the gut microbiome, and other disorders related to both systems. The possible mechanisms of disease are examined for obesity, diabetes, and irritable bowel syndrome as examples of metabolic diseases. Insomnia, narcolepsy, and obstructive sleep apnea as examples of sleep disorders. And hypertension, Alzheimer’s disease, and psychiatric diseases as examples of diseases related to both systems. Understanding of these mechanisms is then used to support probiotics, fecal microbiota transplants, and regulated sleep schedules as potential novel treatments. This research was done to highlight specific reasons why healthy sleep is important and to call attention to another area of human health where the gut microbiome should be considered.

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In Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/ This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).

Persistent Identifier

https://archives.pdx.edu/ds/psu/37720

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