Date of Award
Bachelor of Science (B.S.) in Biology and University Honors
Gut Microbiome, Sleep, Circadian Rhythms, Probiotics, Metabolic Disease
The crosstalk between the gut microbiome and sleep affects many aspects of human health. This paper looks at metabolic disorders affected by sleep deprivation, sleep disorders affected by the gut microbiome, and other disorders related to both systems. The possible mechanisms of disease are examined for obesity, diabetes, and irritable bowel syndrome as examples of metabolic diseases. Insomnia, narcolepsy, and obstructive sleep apnea as examples of sleep disorders. And hypertension, Alzheimer’s disease, and psychiatric diseases as examples of diseases related to both systems. Understanding of these mechanisms is then used to support probiotics, fecal microbiota transplants, and regulated sleep schedules as potential novel treatments. This research was done to highlight specific reasons why healthy sleep is important and to call attention to another area of human health where the gut microbiome should be considered.
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Flikkema, Jessica, "The Relationship Between the Gut Microbiome and Sleep Examined Through Associated Human Disease" (2022). University Honors Theses. Paper 1205.