Advisor

Thelma N. Fisher

Date of Award

7-29-1975

Document Type

Thesis

Degree Name

Master of Science (M.S.) in Biology

Department

Biology

Physical Description

1 online resource. Digitized typeset

Subjects

Fibroblasts, Exfoliative cytology, Prostate

DOI

10.15760/etd.2377

Abstract

The purpose of this investigation was to provide pure cultures of normal human prostatic epithelium free of fibroblasts in order to study malignant conversion by chemical carcinogens. Normal epithelial cells were needed because this was the cell type implicated in prostatic malignancies of human subjects. Unfortunately fibroblasts grew faster than epithelial cells so that cultures were always overgrown with connective tissue elements. It was considered important to find a method which would eliminate fibroblasts so that normal epithelial cells could grow out in pure culture.

Persistent Identifier

http://archives.pdx.edu/ds/psu/15650

Included in

Biology Commons

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