Portland State University. Department of Biology
Date of Publication
Master of Science (M.S.) in Biology
Cardiovascular system, Pregnancy, Cardiology -- Research, Guinea pigs
1 online resource (88 p.)
Maternal cardiovascular adaptations appear to be essential in order to supply extra circulation to both the developing fetus and maternal system during a successful pregnancy. Since inadequate cardiovascular adjustments may produce abortions or maternal morbidity, the characterization of maternal cardiovascular changes during pregnancy and the elaboration of the underlying mechanism for these changes are essential to the understanding of how the heart enlarges during pregnancy and what significance this enlargement might have. To provide needed information regarding this time course and extent of maternal cardiac enlargement and the hormonal and hemodynamic changes which may be responsible for these changes, the guinea pig was used as an animal model to characterize the maternal cardiac, hemodynamic and hormonal changes during early, mid and late pregnancy.
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Hart, Mark Vincent, "Serial cardiovascular adaptations during pregnancy" (1983). Dissertations and Theses. Paper 3354.