Advisor

Jonathan J. Abramson

Date of Award

1992

Document Type

Thesis

Degree Name

Master of Science (M.S.) in Physics

Department

Physics

Physical Description

1 online resource (79 p.)

Subjects

Calcium channels, Calcium in the body, Sarcoplasmic reticulum

DOI

10.15760/etd.6101

Abstract

Calcium ions are important mediators in the mechanism of contraction and relaxation of muscle fibers. Depolarization of sarcolemma and transverse tubule causes an increase of myoplasmic ca2+ concentration which induces contraction of the myofibrils. In skeletal muscle fibers, the intracellular Ca2+ concentraton is regulated by an extensive membrane system, the sarcoplasmic reticulum (SR). Ca2+-release from SR is initiated by depolarization of the transverse tubule via a process referred to as excitation-contraction coupling. The Ca2+ - release channel located in the junctional SR plays an important role in this mechanism.

Description

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Persistent Identifier

http://archives.pdx.edu/ds/psu/24354

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Physics Commons

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