Utility of the 5-minute Apgar Score as a Research Endpoint
American Journal Of Epidemiology
Although Apgar scores are commonly used as proxy outcomes, little evidence exists in support of the most common cutpoints (n= 52,877; 2012–2016), and the other contained hospital births from California (n = 428,877; 2010). We treated 5-minute Apgars as clinical “tests,” compared against 18 known outcomes; we calculated sensitivity, specificity, positive and negative predictive values, and the area under the receiver operating characteristic curve for each. We used 3 different criteria to determine optimal cutpoints. Results were very consistent across data sets, outcomes, and all subgroups: The cutpoint that maximizes the trade-off between sensitivity and specificity is universally
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Bovbjerg, M. L., Dissanayake, M. V., Cheyney, M., Brown, J., & Snowden, J. M. (2019). Utility of the 5-minute Apgar Score as a Research Endpoint. American Journal Of Epidemiology.