Subjects
Molecular spectroscopy, Dyes in medical diagnosis, Biochemical markers -- Synthesis
Abstract
The synthesis and characterization of a new series of long wavelength and NIR-active dyes for use as diagnostic indicators in biological fluids has been carried out. The dyes are synthesized by a one-pot acid promoted condensation and isolated by flash column chromatography. Their structures are assigned by NMR and mass spectrometry. The spectral properties are evaluated by UV-vis and fluorescence spectroscopy. Preliminary spectroscopic data reveal these dyes exhibit anticipated characteristics that apparently meet the current requirements as NIR-active dye candidates for bioimaging and medical applications.
Faculty Mentor: Dr. Robert M. Strongin
DOI
10.15760/mcnair.2012.70
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 International License.
Persistent Identifier
http://archives.pdx.edu/ds/psu/8772
Recommended Citation
Zhao, Jia Li
(2012)
"The Synthesis and Characterization of SNAFR‐5 Derivatives,"
PSU McNair Scholars Online Journal:
Vol. 6:
Iss.
1, Article 12.
https://doi.org/10.15760/mcnair.2012.70