Title

Earlier Diagnosis Not Self-Evidently Beneficial: Natural History of Subcentimeter Lung Cancers

Published In

American Journal Of Roentgenology

Document Type

Citation

Publication Date

5-1-2019

Abstract

OBJECTIVE. We estimated the natural history of subcentimeter stage I non–small cell lung cancers detected on screening CT using a computed mean 230-day tumor volume doubling time and exponential growth.

CONCLUSION. We found that the majority of patients with subcentimeter, non–small cell lung cancers would survive for more than 5 years without treatment. The benefit of cancer interdiction would be offset to some extent by the combined effects of surgical mortality and materially diminished longer-term disease-free survival among the more than 40% of patients who would be overdiagnosed.

Description

Copyright © 2013-2019, American Roentgen Ray Society, ARRS, All Rights Reserved.

DOI

10.2214/AJR.19.21159

Persistent Identifier

https://archives.pdx.edu/ds/psu/29028

Publisher

American Roentgen Ray Society, ARRS

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