Targeted Complexes of Lanthanide(III) Ions as Therapeutic and Diagnostic Pharmaceuticals

Authors

Mark Woods, Portland State UniversityFollow
Zoltan Kovacs, University of Texas Southwestern Medical Center
A. Dean Sherry, University of Texas Southwestern Medical CenterFollow

Published In

Journal of Supramolecular Chemistry

Document Type

Citation

Publication Date

6-2002

Abstract

The physical, magnetic and nuclear properties of the lanthanide ions have rendered them ideal for use in both diagnostic and therapeutic pharmaceuticals. Recent innovations in biotechnology have opened new possibilities for the design of such pharmaceuticals. By conjugating a suitable targeting vector to the metal chelate it may be possible to target tissue type, cell type, individual proteins and even specific nucleic acid sequences. This review describes recent advances in the targeting of these complexes and discusses their potential in the development of new inorganic pharmaceuticals.

Rights

Copyright © 2003 Elsevier Ltd. All rights reserved.

Description

*At the time of publication, Mark Woods was affiliated with the University of Texas at Dallas.

Locate the Document

https://doi.org/10.1016/S1472-7862(02)00072-2

DOI

10.1016/S1472-7862(02)00072-2

Persistent Identifier

https://archives.pdx.edu/ds/psu/36513

Citation Details

Woods, M., Kovacs, Z., & Sherry, A. D. (2002). Targeted complexes of lanthanide (III) ions as therapeutic and diagnostic pharmaceuticals. Journal of Supramolecular Chemistry, 2(1-3), 1-15.