Title
Effects of conalbumin bound iron on the growth of Salmonella paratyphi B and Salmonella thompson
Sponsor
Portland State University. Department of Biology
First Advisor
Mary L. Taylor
Date of Publication
1991
Document Type
Thesis
Degree Name
Master of Science (M.S.) in Biology
Department
Biology
Subjects
Conalbumin, Iron proteins -- Physiological effect, Salmonella, Bacteremia
DOI
10.15760/etd.6265
Physical Description
1 online resource (69 p.)
Abstract
I have investigated the possibility that specific conalbumin (ovotransferrin) iron saturation levels enable less virulent strains of Salmonella to become more virulent. Iron starved cells of two pathogenic Salmonella strains, S. paratyphi B var. java and S. thompson, were cultured in iron limited media at 3 different iron conalbumin saturation levels. Results indicate that strains differ significantly at both low and high iron saturation conalbumin. These differences depict a growth advantage for S. paratyphi B which correlates with reports by the Centers for Disease Control that S. paratyphi B was 3 times more frequent in blood isolates than S. thompson. The ability to use protein bound iron may account for the higher involvement of S. paratyphi B in bacteremia.
Persistent Identifier
https://archives.pdx.edu/ds/psu/25708
Recommended Citation
Mason, John Nicholas, "Effects of conalbumin bound iron on the growth of Salmonella paratyphi B and Salmonella thompson" (1991). Dissertations and Theses. Paper 4381.
https://doi.org/10.15760/etd.6265
Comments
If you are the rightful copyright holder of this dissertation or thesis and wish to have it removed from the Open Access Collection, please submit a request to pdxscholar@pdx.edu and include clear identification of the work, preferably with URL