The Association Between Regular Cannabis Smoking and Oral Human Papillomavirus Infection in Young Adults: A Cross-Sectional Study Using NHANES Data, 2011-2016

Presenter Biography

Jenny and Browning are 4th year students in the MD/MPH program at OHSU-PSU. They are both interested in pursuing Pediatrics and incorporating public health training into their medical practices.

Institution

OHSU

Program/Major

Epidemiology

Degree

MD/MPH

Presentation Type

Presentation

Start Date

4-4-2023 1:30 PM

End Date

4-4-2023 1:45 PM

Persistent Identifier

https://archives.pdx.edu/ds/psu/40234

Keywords

Human papillomavirus, HPV, cannabis, smoking, oral health, NHANES, young adults

Abstract

Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the U.S., and the incidence rates of HPV-related oropharyngeal cancers in the U.S. have doubled in the last 20 years. While cigarette smoking is a known risk factor for oral HPV infection, it is unknown if smoking cannabis is associated with greater occurrence of oral HPV infections. The objective of this study was to estimate the association between cannabis smoking status and oral HPV infection in U.S. young adults ages 18-30 years and examine whether this association differs by HPV vaccination status.

This cross-sectional study used data from the National Health and Nutrition Examination Survey (NHANES) 2011-2016 cycles. Multivariable logistic regression models, stratified by HPV vaccination status, were used to test the association between cannabis smoking status and oral HPV infection.

The final analytic sample (N=2,696) had a mean age of 24.4 (standard error: 0.1) years and most participants were female (50.9%), Non-Hispanic White (59.2%) and unvaccinated against HPV (74.7%). The overall unadjusted prevalence of oral HPV infection was 5.2% (95% CI: 4.1%, 6.5%). Among unvaccinated young adults, and compared to those who do not smoke cannabis, those who regularly smoke cannabis had 3.2 times the odds of oral HPV infection (AOR: 3.2; 95% CI: 1.6, 6.3) and those who irregularly smoke cannabis had 1.5 times the odds of oral HPV infection (AOR: 1.5; 95% CI: 0.8, 3.2).

These findings suggest that smoking cannabis should be further examined in prospective studies as a risk factor for oral HPV infection.

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Apr 4th, 1:30 PM Apr 4th, 1:45 PM

The Association Between Regular Cannabis Smoking and Oral Human Papillomavirus Infection in Young Adults: A Cross-Sectional Study Using NHANES Data, 2011-2016

Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the U.S., and the incidence rates of HPV-related oropharyngeal cancers in the U.S. have doubled in the last 20 years. While cigarette smoking is a known risk factor for oral HPV infection, it is unknown if smoking cannabis is associated with greater occurrence of oral HPV infections. The objective of this study was to estimate the association between cannabis smoking status and oral HPV infection in U.S. young adults ages 18-30 years and examine whether this association differs by HPV vaccination status.

This cross-sectional study used data from the National Health and Nutrition Examination Survey (NHANES) 2011-2016 cycles. Multivariable logistic regression models, stratified by HPV vaccination status, were used to test the association between cannabis smoking status and oral HPV infection.

The final analytic sample (N=2,696) had a mean age of 24.4 (standard error: 0.1) years and most participants were female (50.9%), Non-Hispanic White (59.2%) and unvaccinated against HPV (74.7%). The overall unadjusted prevalence of oral HPV infection was 5.2% (95% CI: 4.1%, 6.5%). Among unvaccinated young adults, and compared to those who do not smoke cannabis, those who regularly smoke cannabis had 3.2 times the odds of oral HPV infection (AOR: 3.2; 95% CI: 1.6, 6.3) and those who irregularly smoke cannabis had 1.5 times the odds of oral HPV infection (AOR: 1.5; 95% CI: 0.8, 3.2).

These findings suggest that smoking cannabis should be further examined in prospective studies as a risk factor for oral HPV infection.