Inequities in chronic stress exposure at the intersection of race, gender, and sexual identity in a nationally representative sample of US adults

Institution

OHSU

Program/Major

Epidemiology

Degree

MPH

Presentation Type

Poster

Start Date

4-4-2024 1:00 PM

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

Keywords

Sexual Identity, Gender, Health Disparaties, Chronic Stress, NHANES

Abstract

Background

Social inequity rooted in systemic oppression is robustly associated with mental and physical health; chronic stress is highlighted as a key mechanism. Limited research examining the association between sexual identity alone and C-reactive protein (CRP) – an upstream biological marker of chronic stress exposure – has yielded mixed results.

Purpose

To examine whether race/ethnicity, gender, and sexual identity interact to produce unequal levels of CRP.

Methods

Using cross-sectional data from the 2003-2010 waves of the National Health and Nutrition Examination Survey, we examined intersectional (self-reported race*gender*sexual identity) patterns in log-transformed CRP levels using a multivariable linear model among 10,885 participants who contributed biospecimen data during their examination. We estimated the percent change in mean log-CRP levels between identity groups when compared to the referent group (straight, non-Hispanic White men).

Results

Mean CRP ranged from 0.16 to 0.89 mg/dL. Relative to straight non-Hispanic White men, mean log-CRP levels were generally higher among women, regardless of race and sexual identity, with Black women identifying as “something else” having the highest percent change in mean log-CRP. Among men, the highest percent change in mean log-CRP were observed for those reporting a sexuality of “something else”.

Conclusion

Across identities, there is evidence of unequal levels of CRP that can contribute to chronic stress. Understanding the intricate interactions between these identities and health is vital for guiding effective interventions. More nuanced approaches to data collection informed by the queer community must be applied to future research to better capture the experiences of these populations.

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Apr 4th, 1:00 PM

Inequities in chronic stress exposure at the intersection of race, gender, and sexual identity in a nationally representative sample of US adults

Background

Social inequity rooted in systemic oppression is robustly associated with mental and physical health; chronic stress is highlighted as a key mechanism. Limited research examining the association between sexual identity alone and C-reactive protein (CRP) – an upstream biological marker of chronic stress exposure – has yielded mixed results.

Purpose

To examine whether race/ethnicity, gender, and sexual identity interact to produce unequal levels of CRP.

Methods

Using cross-sectional data from the 2003-2010 waves of the National Health and Nutrition Examination Survey, we examined intersectional (self-reported race*gender*sexual identity) patterns in log-transformed CRP levels using a multivariable linear model among 10,885 participants who contributed biospecimen data during their examination. We estimated the percent change in mean log-CRP levels between identity groups when compared to the referent group (straight, non-Hispanic White men).

Results

Mean CRP ranged from 0.16 to 0.89 mg/dL. Relative to straight non-Hispanic White men, mean log-CRP levels were generally higher among women, regardless of race and sexual identity, with Black women identifying as “something else” having the highest percent change in mean log-CRP. Among men, the highest percent change in mean log-CRP were observed for those reporting a sexuality of “something else”.

Conclusion

Across identities, there is evidence of unequal levels of CRP that can contribute to chronic stress. Understanding the intricate interactions between these identities and health is vital for guiding effective interventions. More nuanced approaches to data collection informed by the queer community must be applied to future research to better capture the experiences of these populations.