Sensitivity of the Communicative Participation Item Bank for Measuring Patient-Reported Outcomes After Treatment of Unilateral Vocal Fold Immobility

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Jama Otolaryngology-Head & Neck Surgery

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Importance The Communicative Participation Item Bank ( CPIB ) is a patient-reported outcome measure assessing the association between communication disorders and participation in daily communication. To our knowledge, no prior research has examined whether CPIB scores change after treatment of unilateral vocal fold immobility ( UVFI ). Objective To compare CPIB scores before and after treatment of UVFI and with patient-defined target treatment outcomes and other common clinical outcomes after UVFI intervention. Design, Setting, and Participants This single-group case series recruited a convenience sample of community-dwelling patients aged 18 years or older from an urban academic medical center who had a diagnosis of UVFI and planned to receive intervention for UVFI. The study was conducted from March 2014 to March 2019. Exposures Intervention for UVFI according to clinicians’ recommendations. The treatment type was not controlled for this study. Main Outcomes and Measures Patients’ self-reported communicative participation was assessed by obtaining CPIB scores before and after treatment of UVFI, with scores calibrated to the standardized T scale. Pearson correlations between the CPIB general short form and computerized adaptive format, the Voice Handicap Index–10 ( VHI-10 ), and self-rated and clinician-rated voice severity were also evaluated. Results The sample included 25 participants, of whom 17 ( 68% ) were male, 8 ( 32% ) were female, and the mean ( SD ) age was 54.9 ( 17.0 ) years. Significant changes after treatment were observed in all quantitative outcomes including the primary outcome of the CPIB; the mean T score before treatment was 40.95 ( 95 % CI, 37.49-44.41 ) and after treatment was 53.23 ( 95% CI, 48.41-58.04 ) (mean difference, –13.04 [ 95 % CI, −7.30 to −18.79 ]; Cohen d, 0.96). The Pearson correlation between the CPIB general short form and computerized adaptive testing scores at pretreatment was r = 0.93 and at posttreatment, r = 0.95. Computerized adaptive testing showed efficiency advantages, with typically 5 to 6 items required for administration compared with 10 items for the short form. The correlation between the CPIB and VHI-10 was moderate before treatment ( r = −0.70 ) and strong after treatment ( r = −0.91 ). Moderate correlations were observed between the CPIB and clinician-rated voice quality before ( r = −0.52 ) and after ( r = −0.46 ) treatment and between CPIB and self-rated voice quality before ( r = −0.56 ) and after ( r = −0.62 ) treatment. Conclusions and Relevance The results of this case series suggest that the CPIB is relevant for clinical use to assess changes in communicative participation among patients with UVFI before and after they receive treatment.


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