Title

Extreme Sawtooth-Sign in Motor Neuron Disease (MND) Suggests Laryngeal Resistance to Forced Expiratory Airflow

Published In

The Annals of Otology, Rhinology, and Laryngology

Document Type

Citation

Publication Date

4-17-2022

Abstract

The impact of laryngeal dysfunction on airflow has not been well characterized in motor neuron disease (MND). This study aimed to detect and characterize extreme airflow oscillations informally observed during volitional cough and forced vital capacity (FVC) tasks in individuals with MND who demonstrated neurolaryngeal impairments including reduced speed and extent of vocal fold abduction compared to healthy controls during volitional cough expulsion. The extreme airflow oscillations in the MND group, when viewed as a flow-volume loop, appeared similar to the "sawtooth-sign." If the airflow oscillations are periodic in a range similar to phonation, they may reflect reduced laryngeal patency.

Rights

© Sage 2022

DOI

10.1177/00034894221089407

Persistent Identifier

https://archives.pdx.edu/ds/psu/37525

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