Title of Poster / Presentation
Characterizing the Functional Role of Transcription Factor E in Archaeal Transcription
Presentation Type
Poster
Start Date
5-4-2022 11:00 AM
End Date
5-4-2022 1:00 PM
Subjects
Transcription, Protein, Mutations
Advisor
Michael Bartlett
Student Level
Doctoral
Abstract
Archaea and eukaryotes share many homologous proteins and essential mechanisms for survival and DNA replication. It is proposed that Archaea are the ancestors of eukaryotes, suggesting that eukaryotic transcription evolved from the basic archaeal mechanisms. By studying the fundamentals of archaeal transcription, we are in turn understanding more about how eukaryotic transcription functions. Many human diseases are linked to mishaps and mutations in the process of transcribing DNA to mRNA, so it is essential to explore structures and how mutations in these structures affect the essential function of transcription, and if these mutations also play a role in human disease.
Rights
© Copyright the author(s)
IN COPYRIGHT:
http://rightsstatements.org/vocab/InC/1.0/
This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
DISCLAIMER:
The purpose of this statement is to help the public understand how this Item may be used. When there is a (non-standard) License or contract that governs re-use of the associated Item, this statement only summarizes the effects of some of its terms. It is not a License, and should not be used to license your Work. To license your own Work, use a License offered at https://creativecommons.org/
Persistent Identifier
https://archives.pdx.edu/ds/psu/37518
Included in
Characterizing the Functional Role of Transcription Factor E in Archaeal Transcription
Archaea and eukaryotes share many homologous proteins and essential mechanisms for survival and DNA replication. It is proposed that Archaea are the ancestors of eukaryotes, suggesting that eukaryotic transcription evolved from the basic archaeal mechanisms. By studying the fundamentals of archaeal transcription, we are in turn understanding more about how eukaryotic transcription functions. Many human diseases are linked to mishaps and mutations in the process of transcribing DNA to mRNA, so it is essential to explore structures and how mutations in these structures affect the essential function of transcription, and if these mutations also play a role in human disease.