Calibrating an Intracranial Pressure Dynamics Model With Clinical Data - A Progress Report

Authors

Wayne W. Wakeland, Portland State UniversityFollow
James McNames, Portland State UniversityFollow
Brahm Goldstein, Oregon Health & Science UniversityFollow

Sponsor

This work was supported in part by the Thrasher Research Fund

Published In

Proceedings of the 26th Annual International Conference of the IEEE EMBS

Document Type

Post-Print

Publication Date

2004

Subjects

Intracranial pressure -- Measurement, Intracranial pressure -- Computer simulation, Brain damage

Abstract

We describe the calibration of a computer model of intracranial pressure (ICP) dynamics to correspond with annotated clinical data taken from a patient being treated for elevated ICP due to a traumatic brain injury. The research protocol employed during treatment includes adjusting the elevation of the head of the bed, adjusting the ventilator settings to induce mild hyperventilation and hypoventilation, and adjusting the height of the cerebrospinal fluid drainage system. The model behavior corresponds to the experimental data quite well in the case of the changing the head of the bed, but less well in the case of changing the ventilator settings.

Description

This is the authors version of an article accepted for publication. © 2004 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.

The definitive version can be found at the publishers site. https://doi.org/10.1109/IEMBS.2004.140326.

See the additional files below for accompanying Presentation:

26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2004 in San Francisco, California.

DOI

10.1109/IEMBS.2004.1403266

Persistent Identifier

http://archives.pdx.edu/ds/psu/17767

Citation Details

Wakeland, W., Goldstein, B., and McNames, J. Calibrating an Intracranial Pressure Dynamics Model with Annotated Clinical Data--a Progress Report. Presented at the 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2004 in San Francisco, California.