Crosslinked Shells for Nano-Assembled Capsules: A New Encapsulation Method for Smaller Gd(3+)-Loaded Capsules with Exceedingly High Relaxivities

Authors

Annah Farashishiko, Portland State University
Sally E. Plush, University of South AustraliaFollow
Karley B. Maier, Portland State UniversityFollow
A. Dean Sherry, University of Texas at DallasFollow
Mark Woods, Portland State UniversityFollow

Published In

Chemical Communications

Document Type

Citation

Publication Date

5-30-2017

Abstract

Nano-assembled capsules can incorporate large payloads of high relaxivity Gd³⁺, permitting the development of highly detectable molecular imaging agents for MRI. A new encapsulating shell, based upon cross-linked peptides, is found to afford smaller capsules (127 nm average diameter) with exceptionally high per-Gd³⁺ relaxivities (70.7 s⁻¹ mmolal⁻¹).

Description

© The Royal Society of Chemistry 2017

Locate the Document

https://doi.org/10.1039/C7CC00123A

DOI

10.1039/C7CC00123A

Persistent Identifier

http://archives.pdx.edu/ds/psu/20390

Citation Details

Farashishiko, A., Plush, S. E., Maier, K. B., Dean Sherry, A., & Woods, M. (2017). Crosslinked shells for nano-assembled capsules: a new encapsulation method for smaller Gd3+-loaded capsules with exceedingly high relaxivities. Chemical Communications (Cambridge, England), 53(47), 6355-6358.