Crosslinked Shells for Nano-Assembled Capsules: A New Encapsulation Method for Smaller Gd(3+)-Loaded Capsules with Exceedingly High Relaxivities
Nano-assembled capsules can incorporate large payloads of high relaxivity Gd3+, permitting the development of highly detectable molecular imaging agents for MRI. A new encapsulating shell, based upon cross-linked peptides, is found to afford smaller capsules (127 nm average diameter) with exceptionally high per-Gd3+ relaxivities (70.7 s−1 mmolal−1).
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Farashishiko, A., Plush, S. E., Maier, K. B., Dean Sherry, A., & Woods, M. (2017). Crosslinked shells for nano-assembled capsules: a new encapsulation method for smaller Gd3+-loaded capsules with exceedingly high relaxivities. Chemical Communications (Cambridge, England), 53(47), 6355-6358.