Aggregation in Amphiphilic Macrocycle Substituted Gd3+ DOTA-type Chelates is Affected by the Regiochemistry of Substitution

Authors

Benjamin C. Webber, Portland State UniversityFollow
Claudio Cassino, Università del Piemonte Orientale
Mauro Botta, Università del Piemonte Orientale
Mark Woods, Portland State UniversityFollow

Published In

Inorganic Chemistry

Document Type

Citation

Publication Date

2015

Abstract

Gd(3+) chelates of macrocyclic bifunctional chelators (BFCs) can differentiate into two regioisomers: corner and side. These isomers afford different orientations of chelate relative to conjugate. These differences alter the self-assembly, tumbling, and effectiveness as magnetic resonance imaging contrast agents of the two biphenyl conjugate isomers.

Description

Copyright © 2015 American Chemical Society

Locate the Document

https://doi.org/10.1021/ic5028724

DOI

10.1021/ic5028724

Persistent Identifier

https://archives.pdx.edu/ds/psu/31026

Citation Details

Webber, B. C., Cassino, C., Botta M.,, and Woods, M. (2015). Aggregation in Amphiphilic Macrocycle Substituted Gd3+ DOTA-type Chelates is Affected by the Regiochemistry of Substitution. Inorg. Chem., (2015), 54, 2085–2087.