Title

LDL-Based Nanoparticles for Contrast Enhanced MRI of Atheroplaques in Mouse Models

Published In

Chemical Communication

Document Type

Citation

Publication Date

2011

Abstract

A LDL particle functionalized with a GdDO3A-monoamidechelate with a long alkenyl anchor (GdDO3A-OA) was preparedforin vivodetection of atheroplaques. The GdDO3A-OA, whensuccessfully intercalated into the lipid layer of LDL particles, ledto a significant enhancement of magnetic resonance imaging signalintensity of atheroplaques in atherosclerosis mouse models.

Description

This journal is copyrighted The Royal Society of Chemistry 2011

DOI

10.1039/C1CC10924C

Persistent Identifier

https://archives.pdx.edu/ds/psu/32343

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