Published In

Chemistry & Biology

Document Type

Article

Publication Date

4-2012

Subjects

RNA -- Biology, RNA -- Evolution, Evolutionary genetics

Abstract

When RNA is replicated in cell-free systems, a ubiquitous problem is the hijacking of the system by short parasitic RNA sequences. In this issue of Chemistry & Biology, Bansho et al. show that compartmentalization into water-in-oil droplets can ameliorate this problem, but only if the droplets are small. This result helps to both recapitulate abiogenesis and optimize synthetic biology.

Refers to: Bansho, Yohsuke, et al. "Importance of Parasite RNA Species Repression for Prolonged Translation-Coupled RNA Self-Replication." Chemistry & Biology 19.4 (2012): 478-487.

Description

Copyright 2012 Elsevier Ltd All rights reserved

This is an Elsevier Open Archive preview article reproduced. Originally published here http://dx.doi.org/10.1016/j.chembiol.2012.04.002.

DOI

10.1016/j.chembiol.2012.04.002

Persistent Identifier

http://archives.pdx.edu/ds/psu/10529

Download

Share

COinS