Published In

American Journal of Public Health

Document Type

Post-Print

Publication Date

2015

Subjects

Antioxidants -- Health aspects -- United States, Blood pressure -- Research -- case studies

Abstract

Objectives—We assessed 2 pathways through which dietary antioxidants may counter adverse effects of exposure to particulate matter less than 2.5 micrometers in diameter (PM2.5) on blood pressure (BP): main (compensatory) and modifying (protective) models. Methods—We used 2002 to 2003 data from the Detroit Healthy Environments Partnership community survey conducted with a multiethnic sample of adults (n = 347) in low- to moderate-income, predominantly Hispanic and non-Hispanic Black neighborhoods in Detroit, Michigan. We used generalized estimating equations to test the effects of ambient exposure to PM2.5 and dietary antioxidant intake on BP, with adjustment for multiple confounders. Results—Dietary antioxidant intake was inversely associated with systolic BP (b = −0.5; P < .05)and pulse pressure (b = −0.6; P < .05) in neighborhoods closest to major sources of airpollutants. Adverse effects of PM2.5 remained significant after accounting for antioxidant intakes. Exploratory analyses suggested potential modifying effects of antioxidant intake on associations between ambient PM2.5 exposure and BP.

Description

This is the author's version of an article which was subsequently published in the American Journal of Public Health, 105(6), 1254-1261.

Copyright (2015) American Public Health Association

Version of record can be found at:

http://ajph.aphapublications.org/doi/abs/10.2105/AJPH.2014.302176

DOI

10.2105/AJPH.2014.302176

Persistent Identifier

http://archives.pdx.edu/ds/psu/16507

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