Sponsor
The present study was supported in part by the National Sciences Council, Executive Yuan (Grant Number NSC 100-2621-M-039-001), the Buddhist Dalin Tzu Chi Hospital (Grant Number DTCRD101-E-08), the China Medical University Hospital (Grant Number 1MS1), the Department of Health of Taiwan, the Clinical Trial and Research Center for Excellence (Grant Number DOH101-TD-B-111-004), and the Cancer Research Center of Excellence (DOH101-TD-C-111-005).
Published In
BMC Public Health
Document Type
Article
Publication Date
10-19-2013
Subjects
Chronic obstructive pulmonary disease - Depression
Abstract
Background
Depression is a common and mostly undertreated problem in patients with chronic diseases. However, population-based studies on the association between chronic obstructive pulmonary disease (COPD) and subsequent depression are limited in Asian populations. This study evaluated the incidence and risk factors of depression for patients with COPD in Taiwan.
Methods
Using the claims data from the National Health Insurance of Taiwan, we identified 38,010 COPD patients newly diagnosed in 2000–2004 and 38,010 subjects without COPD frequency, matched by sex, age and index date. The incidence rate and hazard ratio for depression were estimated by the end of 2008.
Results
The incidence rate of depression was 1.88 folds higher in the COPD cohort than in the non-COPD cohort (12.2 versus 6.47 per 1,000 person-years, p < 0.0001). The depression risk was the greatest within the first year following COPD diagnosis and tended to decline with follow-up time. Among COPD patients, multivariate analysis showed that younger women and low-income patients were at higher risk of depression. Hospitalization and comorbidities such as hypertension, arthritis, cancer, and heart disease were also significant predictors for depression risk.
Conclusion
This population-based cohort study demonstrated a strong relationship between COPD and subsequent depression. These findings could assist healthcare providers to pinpoint individuals with a higher predisposition to having depression, which could then facilitate the provision of culturally appropriate rehabilitation within the first year after the diagnosis of COPD.
Rights
Copyright 2013 Tsai et al.; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
DOI
10.1186/1471-2458-13-976
Persistent Identifier
http://archives.pdx.edu/ds/psu/10178
Citation Details
Tsai, T. Y., Livneh, H., Lu, M. C., Tsai, P. Y., Chen, P. C., & Sung, F. C. (2013). Increased risk and related factors of depression among patients with COPD: a population-based cohort study. BMC public health, 13(1), 976.
Description
The electronic version of this article is the complete one and can be found online at:http://www.biomedcentral.com/1471-2458/13/976