Sponsor
We gratefully acknowledge the support of the Wallace H. Coulter Foundation through the Early Career Award for Translational Research.
Published In
Optics Express
Document Type
Article
Publication Date
4-17-2008
Subjects
Image processing -- Digital techniques, Optical data processing
Abstract
We introduce a new multi aperture system capable of capturing six identical images of the human fundus at six different spectral bands. The system is based on a lenslet array architecture and is well suited for spectroscopy application. The multi-aperture system was interfaced with a fundus camera to acquire spectroscopic sensitive images of the retina vessel and ultimately to calculate oxygen saturation in the retina in vivo. In vitro testing showed that the system is able to accurately reconstruct curves of partially oxygenated hemoglobin. In vivo testing on healthy volunteers was conducted and yielded results of oxygen saturation similar to the one reported in the literature, with arterial SO2 ~0.95 and venous SO2 ~ 0.5.
DOI
10.1364/OE.16.006170
Persistent Identifier
http://archives.pdx.edu/ds/psu/7286
Citation Details
Jessica C. Ramella-Roman, Scott A. Mathews, Haripriya Kandimalla, Afshin Nabili, Donald D. Duncan, Salvatore A. D'Anna, Syed M. Shah, and Quan D. Nguyen, "Measurement of oxygen saturation in the retina with a spectroscopic sensitive multi aperture camera," Opt. Express 16, 6170-6182 (2008)
Description
This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/oe/viewmedia.cfm?uri=oe-16-9-6170&seq=0. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.