Sponsor
This work was sponsored in part by National Institutes of Health Grant No. RO1 EY017577.
Published In
Journal of Biomedical Optics
Document Type
Article
Publication Date
10-6-2010
Subjects
Radon transforms, Perfusion (Physiology)
Abstract
We present a new method for the quantitative estimation of blood flow velocity, based on the use of the Radon transform. The specific application is for measurement of blood flow velocity in the retina. Our modified fundus camera uses illumination from a green LED and captures imagery with a high-speed CCD camera. The basic theory is presented, and typical results are shown for an in vitro flow model using blood in a capillary tube. Subsequently, representative results are shown for representative fundus imagery. This approach provides absolute velocity and flow direction along the vessel centerline or any lateral displacement therefrom. We also provide an error analysis allowing estimation of confidence intervals for the estimated velocity.
DOI
10.1117/1.3494565
Persistent Identifier
http://archives.pdx.edu/ds/psu/7289
Citation Details
Donald D. Duncan, Paul Lemaillet, Mohamed Ibrahim, Quan Dong Nguyen, Matthias Hiller and Jessica Ramella-Roman, (2010). "Absolute blood velocity measured with a modified fundus camera", J. Biomed. Opt. 15, 056014. http://dx.doi.org/10.1117/1.3494565
Description
This is the publisher's final PDF. Copyright 2010 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.