Sponsor
The validation study was sponsored by Biogen and Pfizer. The Alexander von Humboldt Foundation provided a grant for study equipment. Clario funded the study via the employment of JM, VVS, ME-G, KLS, and FBH at APDM Wearable Technologies of Clario.
Published In
The Lancet. Digital Health
Document Type
Article
Publication Date
10-16-2025
Subjects
Spinocerebellar ataxia -- Clinical Trials
Abstract
Clinical trials in spinocerebellar ataxia are currently limited by the large sample sizes required by available clinical endpoints. We aimed to devise a digital composite measure of standing and walking balance using wearable inertial sensors that would require smaller sample sizes. The new score is called the Score of Integrated Balance in Ataxia (SIBA).
Rights
Copyright © 2025 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Locate the Document
DOI
10.1016/j.landig.2025.100905
Persistent Identifier
https://archives.pdx.edu/ds/psu/44210
Publisher
Elsevier BV
Citation Details
McNames, J., Shah, V. V., Casey, H. L., Sowalsky, K. L., El-Gohary, M., Safarpour, D., Carlson-Kuhta, P., Schmahmann, J. D., Rosenthal, L. S., Perlman, S., Rodríguez-Labrada, R., Velázquez-Pérez, L., Horak, F. B., & Gomez, C. M. (2025). Development and validation of a composite digital balance score for spinocerebellar ataxia: a prospective study. The Lancet Digital Health, 7(9), 100905.