First Advisor

Radhika Reddy

Date of Award

Spring 6-14-2026

Document Type

Thesis

Degree Name

Bachelor of Science (B.S.) in Science and University Honors

Department

Science

Language

English

Subjects

neuroplasticity, traumatic brain injury, cognitive enrichment, neuroimaging

DOI

10.15760/honors.1851

Abstract

This meta-analysis evaluated whether cognitive enrichment and targeted learning interventions result in greater structural and cognitive recovery than standard care among adults with traumatic brain injury (TBI). The study examined both neuroimaging and behavioral outcomes, with particular emphasis on recovery beyond six months post-injury and the involvement of the ventromedial prefrontal cortex. Overall, the interventions produced significantly greater improvements than standard care, especially in individuals assessed more than six months after injury. Notable benefits were observed in measures of gray and white matter integrity. However, correlation-based measures yielded inconsistent findings. Collectively, the results suggest that structured cognitive interventions are more effective than standard care in enhancing neuroimaging outcomes and promoting measurable recovery-related changes.

Comments

An undergraduate honors thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Science, Psychology, and Liberal Studies, Minor in Biology and Interdisciplinary Neuroscience

Persistent Identifier

https://archives.pdx.edu/ds/psu/44785

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Available for download on Friday, June 02, 2028

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