First Advisor
Jong Kim
Date of Award
2016
Document Type
Thesis
Degree Name
Bachelor of Arts (B.A.) in Mathematics and University Honors
Department
Mathematics
Subjects
Retinal degeneration, Multiple sclerosis, Nervous system -- Degeneration
DOI
10.15760/honors.235
Abstract
Patients with multiple sclerosis (MS) have long been known to suffer deterioration of the retina, sometimes leading to blindness. The damage has been assumed to occur predominantly within the retinal nerve fiber layer. Using optical coherence tomography (OCT), researchers at Johns Hopkins University have determined that there is a subset of MS patients for whom the retinal deterioration is different. For this group the deterioration occurs at a deeper level within the retina, between the photoreceptors and the connecting cells. This deterioration affects the inner and outer nuclear layers of the retina. These findings are perplexing, as MS is considered primarily a demyelinating disease, and the retinal cell structures are unmyelinated.
Rights
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Persistent Identifier
http://archives.pdx.edu/ds/psu/17308
Recommended Citation
Festner, Zac, "Understanding Multiple Sclerosis Through Retinal Cell Layer Thickness: An Insight into the Neurodegeneration Process" (2016). University Honors Theses. Paper 245.
https://doi.org/10.15760/honors.235