First Advisor

Jeffrey D. Robinson

Date of Award

6-14-2019

Document Type

Thesis

Degree Name

Bachelor of Science (B.S.) in Biology and University Honors

Department

Biology

Subjects

Diabetes -- Treatment, Behavior modification, Blood sugar monitoring, Patient compliance

DOI

10.15760/honors.773

Abstract

Uncontrolled type 1 diabetes puts adolescents at an increased risk for cardiovascular disease, retinopathy, neuropathy, reduced brain mass, and reduced life expectancy among other symptoms. Clinically, behavioral interventions are staged for patients with uncontrolled type 1 diabetes. Meta-analyses of these interventions have yielded non-significant differences in overall glycemic control, and have yet to identify any significant moderators of outcomes. The goal of this study was to update and improve upon past meta-analyses, and evaluate potential moderators. 28 RCTs of behavioral interventions in type 1 diabetes evaluating glycemic control were identified. Variables within interventions were collected and reviewed systematically, separating interventions into groups based on operational intensity, and time investment. Significant differences in effect size between groups separated by intervention administrator, training of administrators, and contact time were observed, marking those variables as potential effect moderators. However, more stringent meta-analytic tests concluded no evidence for moderation by any of the identified variables. Future studies regarding the science of intervention development should aim to limit demographic variance, and identify articles with large sample sizes, in order to discover significant moderators in improving glycemic control within behavioral type 1 diabetes interventions.

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In Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/ This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).

Persistent Identifier

https://archives.pdx.edu/ds/psu/29033

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