First Advisor

Robert G. Martindale

Date of Award

3-26-2021

Document Type

Thesis

Degree Name

Bachelor of Arts (B.A.) in Public Health Studies: Pre-clinical Health Science and University Honors

Department

Health Studies

Language

English

Subjects

Cachexia -- Etiology, Cancer -- Nutritional aspects, Cancer -- Complications, Malnutrition -- Treatment

DOI

10.15760/honors.988

Abstract

Despite significant advances in oncologic treatment, underlying cancer-associated metabolic derangements and nutritional needs remain largely neglected in cancer care. Cancer cachexia and protective metabolic changes exhibited by cancerous cells continue to pose formidable barriers to improving therapeutic outcomes and quality of life for patients. Cancer has traditionally been viewed as a proliferative disease caused by genetic mutations, but newer perspectives suggest that it is primarily a metabolic disease. The present paper discusses the etiology of cachexia and sarcopenia, and nutritional interventions that can be offered to patients suffering from these wasting disorders. The role of inflammation in cancer and the methods for preventing and resolving it with nutrition are also explored. Ultimately, a number of nutritional recommendations aimed at overcoming cachexia, resolving inflammation and improving cancer outcomes are provided based on a review of the current literature.

Rights

In Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/ This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).

Persistent Identifier

https://archives.pdx.edu/ds/psu/35016

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