Sponsor
Portland State University. Department of Chemistry
First Advisor
Joann S. Loehr
Term of Graduation
Fall 1977
Date of Publication
12-2-1977
Document Type
Thesis
Degree Name
Master of Science (M.S.) in Chemistry
Department
Chemistry
Language
English
Subjects
Proteins, Thiols, Binding sites (Biochemistry)
DOI
10.15760/etd.2470
Physical Description
1 online resource (3, 42 pages)
Abstract
Hemerythrin is a respiratory protein found in the erythrocytes of certain marine invertebrates. Structures have been obtained by x-ray crystallography for hemerythrins from Phascolopsis gouldii (P. gouldii) and Themiste dyscritum (T. dyscritum). Since many proteins are inactivated upon binding heavy metals such as mercury, an investigation of mercury-protein interactions in this protein was undertaken. In order to understand the nature of heavy-metal protein interactions in T. dyscritum it was necessary to identify the metalloprotein ligands since neither the liganding amino acid residues nor the geometry of the mercury complexes could be identified in the crystallographic studies.
Rights
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Persistent Identifier
https://archives.pdx.edu/ds/psu/15899
Recommended Citation
Clarke, Suzanne Elizabeth, "Involvement of Hemerythrin Sulfhydryl Groups in Heavy Atom Binding and Subunit Interactions" (1977). Dissertations and Theses. Paper 2473.
https://doi.org/10.15760/etd.2470