Date of Award

1977

Document Type

Thesis

Degree Name

Master of Science (M.S.) in Chemistry

Department

Chemistry

Physical Description

1 online resource (50 p.)

Subjects

Hemerythrin, Proteins, Thiols, Binding sites (Biochemistry)

DOI

10.15760/etd.2470

Abstract

Hemerythrin is a respiratory protein found in the erythrocytes of certain marine invertebrates. Structures have been obtained by x-ray crystallography for hemerythrins from Phascolopsis gouldii (P. gouldii) and Themiste dyscritum (T. dyscritum). Since many proteins are inactivated upon binding heavy metals such as mercury, an investigation of mercury-protein interactions in this protein was undertaken. In order to understand the nature of heavy-metal protein interactions in T. dyscritum it was necessary to identify the metalloprotein ligands since neither the liganding amino acid residues nor the geometry of the mercury complexes could be identified in the crystallographic studies.

Description

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Chemistry

Persistent Identifier

http://archives.pdx.edu/ds/psu/15899

Included in

Chemistry Commons

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