First Advisor

Robert M. Strongin

Term of Graduation

Spring 2008

Date of Publication

6-6-2008

Document Type

Dissertation

Degree Name

Doctor of Philosophy (Ph.D.) in Chemistry

Department

Chemistry

Language

English

Subjects

Biochemical markers, Chemical detectors, Polymer colloids

DOI

10.15760/etd.7997

Physical Description

1 online resource (vii, 110 pages)

Abstract

Chemomechanical polymer gels with the capability of recognizing specific biological molecules are promising materials for many biomedical applications. Glucose-selective hydrogels have potential utility in the continuous monitoring of glucose and glucose-triggered insulin delivery for the management of diabetes. Herein, the development and study of the first material which detects glucose via significant volume changes in the challenging matrix human blood plasma is described. The material was created via the modification of PMMA with supramolecular binding sites. The polymer exhibits excellent selectivity and reversibility including continuous expansion-contraction cycles.

Rights

In Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/

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Comments

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Persistent Identifier

https://archives.pdx.edu/ds/psu/38583

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