Portland State University. Department of Chemistry
Robert M. Strongin
Term of Graduation
Date of Publication
Doctor of Philosophy (Ph.D.) in Chemistry
Biochemical markers, Chemical detectors, Polymer colloids
1 online resource (vii, 110 pages)
Chemomechanical polymer gels with the capability of recognizing specific biological molecules are promising materials for many biomedical applications. Glucose-selective hydrogels have potential utility in the continuous monitoring of glucose and glucose-triggered insulin delivery for the management of diabetes. Herein, the development and study of the first material which detects glucose via significant volume changes in the challenging matrix human blood plasma is described. The material was created via the modification of PMMA with supramolecular binding sites. The polymer exhibits excellent selectivity and reversibility including continuous expansion-contraction cycles.
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Samoei, George Kiplimo, "Development and Investigation of Unique Organic Materials to Detect Disease Biomarkers" (2008). Dissertations and Theses. Paper 6137.