Mental-Somatic Multimorbidity in Trajectories of Cognitive Function for Middle-Aged and Older Adults

Authors

Siting Chen, OHSU-PSU School of Public Health
Corey L. Nagel, University of Arkansas for Medical Sciences
Ruotong Liu, Oregon Health & Science University
Anda Botoseneanu, The University Of Michigan
Heather G. Allore, Yale University
Jason T. Newsom, Portland State University
Stephen Thielke, University of Washington
Jeffrey Kaye, Portland State University
Ana R. Quiñones, OHSU-PSU School of Public Health

Sponsor

This work was supported by the National Institute on Aging at the National Institutes of Health (grant numbers RF1AG058545 to ARQ; HGA who contributed from the Yale Claude D. Pepper Older Americans Independence Center P30AG021342 and Yale Alzheimer's Disease Research Center P30AG066508; P30AG066518, and P30AG024978 to JK).

Published In

Plos One

Document Type

Article

Publication Date

5-14-2024

Subjects

Older Adults -- Multimorbidity

Abstract

Multimorbidity may confer higher risk for cognitive decline than any single constituent disease. This study aims to identify distinct trajectories of cognitive impairment probability among middle-aged and older adults, and to assess the effect of changes in mental-somatic multimorbidity on these distinct trajectories.

Rights

Copyright: © 2024 Chen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Locate the Document

https://doi.org/10.1371/journal.pone.0303599

DOI

10.1371/journal.pone.0303599

Persistent Identifier

https://archives.pdx.edu/ds/psu/41832

Citation Details

Chen, S., Nagel, C. L., Liu, R., Botoseneanu, A., Allore, H. G., Newsom, J. T., Thielke, S., Kaye, J., & Quiñones, A. R. (2024). Mental-somatic multimorbidity in trajectories of cognitive function for middle-aged and older adults. PLOS ONE, 19(5), e0303599.