'Lady Windermere's counterpart? Pulmonary nontuberculous mycobacteria in men with bronchiectasis
Published In
Diagnostic Microbiology and Infectious Disease
Document Type
Citation
Publication Date
2-2020
Abstract
Pulmonary nontuberculous mycobacterial (NTM) disease occurs frequently in older women, and phenotypes of men with NTM disease are largely undescribed. We conducted a case–control study of 34 men with non-cystic fibrosis pulmonary NTM disease (cases), and three male and female control groups with or without NTM disease. Cases were median 71 years of age (range 30–94) and mostly non-Hispanic white (85.3%). These men had similarly low BMI as their female NTM patient counterparts, which was lower than both healthy men (p < 0.001) and bronchiectatic men without NTM (p = 0.06). Kyphoscoliosis was also more common in cases than healthy men (p= 0.007) or bronchiectatic men without NTM (p = 0.02). Our study was the first study to our knowledge to examine demographic features and phenotypes of men with NTM disease. Larger studies are needed to ascertain whether these phenotypes are characteristic of men with NTM disease.
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Persistent Identifier
https://archives.pdx.edu/ds/psu/33398
Citation Details
Jennifer H. Ku, Gregory Ranches, Sarah A.R. Siegel, Kevin L. Winthrop, ‘Lady Windermere's counterpart? Pulmonary nontuberculous mycobacteria in men with bronchiectasis, Diagnostic Microbiology and Infectious Disease, Volume 96, Issue 2, 2020, 114916, ISSN 0732-8893, https://doi.org/10.1016/j.diagmicrobio.2019.114916. (http://www.sciencedirect.com/science/article/pii/S073288931930642X) Abstract: Pulmonary nontuberculous mycobacterial (NTM) disease occurs frequently in older women, and phenotypes of men with NTM disease are largely undescribed. We conducted a case–control study of 34 men with non-cystic fibrosis pulmonary NTM disease (cases), and three male and female control groups with or without NTM disease. Cases were median 71 years of age (range 30–94) and mostly non-Hispanic white (85.3%). These men had similarly low BMI as their female NTM patient counterparts, which was lower than both healthy men (p < 0.001) and bronchiectatic men without NTM (p = 0.06). Kyphoscoliosis was also more common in cases than healthy men (p= 0.007) or bronchiectatic men without NTM (p = 0.02). Our study was the first study to our knowledge to examine demographic features and phenotypes of men with NTM disease. Larger studies are needed to ascertain whether these phenotypes are characteristic of men with NTM disease. Keywords: Atypical mycobacteria; Nontuberculous mycobacteria; Pulmonary infection; Bronchiectasis; Kyphoscoliosis; Pectus excavatum
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