Treatment Guidelines and Early Loss from Care for People Living with HIV in Cape Town, South Africa: A Retrospective Cohort Study

Authors

Ingrid T. Katz, Division of Women’s Health, Brigham and Women’s HospitalFollow
Richard Kaplan, University of Cape Town Medical School
Garrett Fitzmaurice, McLean HospitalFollow
Dominick Leone, MIT and HarvardFollow
David R. Bangsberg, Portland State UniversityFollow
Linda-Gail Bekker, University of Cape Town Medical School
Catherine Orrell, University of Cape TownFollow

Sponsor

U.S. National Institute for Mental Health K23 MH097667.

Published In

PLoS Medicine

Document Type

Article

Publication Date

11-14-2017

Subjects

Antiretroviral treatment -- Initiation, Patient refusal of treatment, HIV infections -- South Africa -- Treatment

Abstract

South Africa has undergone multiple expansions in antiretroviral therapy (ART) eligibility from an initial CD4+ threshold of ≤200 cells/μl to providing ART for all people living with HIV (PLWH) as of September 2016. We evaluated the association of programmatic changes in ART eligibility with loss from care, both prior to ART initiation and within the first 16 weeks of starting treatment, during a period of programmatic expansion to ART treatment at CD4+ ≤ 350 cells/μl.

Description

Copyright: © 2017 Katz et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

DOI

10.1371/journal.pmed.1002434

Persistent Identifier

http://archives.pdx.edu/ds/psu/22656

Citation Details

Katz, I. T., Kaplan, R., Fitzmaurice, G., Leone, D., Bangsberg, D. R., Bekker, L. G., & Orrell, C. (2017). Treatment guidelines and early loss from care for people living with HIV in Cape Town, South Africa: A retrospective cohort study. PLoS medicine, 14(11), e1002434.