U.S. National Institute for Mental Health K23 MH097667.
Antiretroviral treatment -- Initiation, Patient refusal of treatment, HIV infections -- South Africa -- Treatment
South Africa has undergone multiple expansions in antiretroviral therapy (ART) eligibility from an initial CD4+ threshold of ≤200 cells/μl to providing ART for all people living with HIV (PLWH) as of September 2016. We evaluated the association of programmatic changes in ART eligibility with loss from care, both prior to ART initiation and within the first 16 weeks of starting treatment, during a period of programmatic expansion to ART treatment at CD4+ ≤ 350 cells/μl.
Katz, I. T., Kaplan, R., Fitzmaurice, G., Leone, D., Bangsberg, D. R., Bekker, L. G., & Orrell, C. (2017). Treatment guidelines and early loss from care for people living with HIV in Cape Town, South Africa: A retrospective cohort study. PLoS medicine, 14(11), e1002434.