Treatment and Prevention of Opioid Use Disorder: Challenges and Opportunities

Authors

Dennis McCarty, Oregon Health & Science University-OHSU-PSU School of Public HealthFollow
Kelsey C. Priest, Oregon Health & Science University-OHSU-PSU School of Public HealthFollow
P. Todd Korthuis, Oregon Health & Science University-OHSU-PSU School of Public HealthFollow

Published In

Annual Review of Public Health

Document Type

Post-Print

Publication Date

12-22-2017

Subjects

Opioids -- Therapeutic use, Opioid abuse -- Treatment, Buprenorphine--Therapeutic use, Opiods -- Antagonists, Naloxone -- Therapeutic use, Opioids -- Overdose -- United States -- Prevention

Abstract

Treatment for opioid use disorder in the United States evolved in response to changing federal policy and advances in science. Inpatient care began in 1935 with the US Public Health Service Hospitals in Lexington, Kentucky, and Fort Worth, Texas. Outpatient clinics emerged in the 1960s to provide aftercare. Research advances led to opioid agonist and opioid antagonist therapies. When patients complete opioid withdrawal, return to use is often rapid and frequently deadly. US and international authorities recommend opioid agonist therapy (i.e., methadone or buprenorphine). Opioid antagonist therapy (i.e., extended-release naltrexone) may also inhibit return to use. Prevention efforts emphasize public and prescriber education, use of prescription drug monitoring programs, and safe medication disposal options. Overdose education and naloxone distribution promote access to rescue medication and reduce opioid overdose fatalities. Opioid use disorder prevention and treatment must embrace evidence-based care and integrate with physical and mental health care.

Description

Copyright 2018 Dennis McCarty et al. This work is licensed under a Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See credit lines of images or other third-party material in this article for license information.

Review in Advance first posted online on December 22, 2017. (Changes may still occur before final publication.)
https://doi.org/10.1146/annurev-publhealth-040617-013526.

DOI

10.1146/annurev-publhealth-040617-013526

Persistent Identifier

http://archives.pdx.edu/ds/psu/23152

Publisher

Annual Reviews

Citation Details

McCarty, D., Priest, K. C., & Korthuis, P. T. (2017). Treatment and Prevention of Opioid Use Disorder: Challenges and Opportunities. Annual review of public health, (0).