Validation of Sleep Questionnaires in the Down syndrome Population
Presentation Type
Poster
Start Date
5-4-2022 11:00 AM
End Date
5-4-2022 1:00 PM
Subjects
OSA, Down syndrome, sleep apnea, validation, questionnaires
Other
OHSU Otolaryngology - Head and Neck Surgery
Advisor
Derek Lam
Student Level
Undergraduate
Other
Clinical Outcomes
Abstract
Introduction/Research Significance: Obstructive Sleep Apnea (OSA) is highly prevalent in the pediatric down syndrome population. In the non-syndromic population, the prevalence is about 1-5% whereas in the syndromic population, the prevalence is 50-100%. Sleep questionnaires are often used to screen for OSA, but these questionnaires have not yet been validated within the down syndrome population.
Methods: A prospective cohort study was conducted to validate two sleep apnea-related questionnaires among children with down syndrome between the ages of 2 and 18 years old. Patients were enrolled through the Down Syndrome clinic at Oregon Health and Science University from 12/17/2020 to 02/11/2022. Caregivers were asked to complete the Pediatric Sleep Questionnaire (PSQ, a sleep apnea screening questionnaire), OSA-18 (a sleep apnea specific quality of life questionnaire), and the PedsQL (a generic quality of life questionnaire) and were asked to complete an overnight sleep study. PSQ and OSA-18 scores were compared to the sleep study and PedsQL results, respectively to calculate sensitivity, specificy, and positive and negative predictive values.
Conclusion: Preliminary data demonstrate that these questionnaires perform similarly in children with Down Syndrome as in the general pediatric population. Additional data from an independent sample will be assessed to confirm these findings.
Rights
© Copyright the author(s)
IN COPYRIGHT:
http://rightsstatements.org/vocab/InC/1.0/
This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
DISCLAIMER:
The purpose of this statement is to help the public understand how this Item may be used. When there is a (non-standard) License or contract that governs re-use of the associated Item, this statement only summarizes the effects of some of its terms. It is not a License, and should not be used to license your Work. To license your own Work, use a License offered at https://creativecommons.org/
Persistent Identifier
https://archives.pdx.edu/ds/psu/37513
Validation of Sleep Questionnaires in the Down syndrome Population
Introduction/Research Significance: Obstructive Sleep Apnea (OSA) is highly prevalent in the pediatric down syndrome population. In the non-syndromic population, the prevalence is about 1-5% whereas in the syndromic population, the prevalence is 50-100%. Sleep questionnaires are often used to screen for OSA, but these questionnaires have not yet been validated within the down syndrome population.
Methods: A prospective cohort study was conducted to validate two sleep apnea-related questionnaires among children with down syndrome between the ages of 2 and 18 years old. Patients were enrolled through the Down Syndrome clinic at Oregon Health and Science University from 12/17/2020 to 02/11/2022. Caregivers were asked to complete the Pediatric Sleep Questionnaire (PSQ, a sleep apnea screening questionnaire), OSA-18 (a sleep apnea specific quality of life questionnaire), and the PedsQL (a generic quality of life questionnaire) and were asked to complete an overnight sleep study. PSQ and OSA-18 scores were compared to the sleep study and PedsQL results, respectively to calculate sensitivity, specificy, and positive and negative predictive values.
Conclusion: Preliminary data demonstrate that these questionnaires perform similarly in children with Down Syndrome as in the general pediatric population. Additional data from an independent sample will be assessed to confirm these findings.