Using Optimization to Calibrate Models of Intracranial Pressure Dynamics to Patients with Intracranial Hypertension

Authors

Wayne W. Wakeland, Portland State UniversityFollow
A. Bulbul, Portland State UniversityFollow
Mateo Aboy, Portland State UniversityFollow
James McNames, Portland State UniversityFollow
Brahm Goldstein, Oregon Health & Science UniversityFollow

Sponsor

This work was supported in part by the Thrasher Research Fund

Document Type

Poster

Publication Date

2004

Subjects

Intracranial pressure, Biology -- Research, Brain Concussion

Abstract

Aim: Automatically calibrate ICP Dynamic model to a specific patients.

Method: Use optimization algorithm to estimate parameter values (ICP, compliances, resistances) that minimize the squared error in predicted ICP.

Results: Estimated parameter values are plausible and improve predicted ICP. Optimization time for 18 minute episode = 2.5 min. for 1 parameter, 10 to 200 min. for multiple simultaneous parameters (too long).

Persistent Identifier

http://archives.pdx.edu/ds/psu/17766

Citation Details

Wakeland, Wayne W.; Bulbul, A.; Aboy, Mateo; McNames, James; and Goldstein, Brahm, "Using Optimization to Calibrate Models of Intracranial Pressure Dynamics to Patients with Intracranial Hypertension" (2004). Systems Science Faculty Publications and Presentations. 87.
http://archives.pdx.edu/ds/psu/17766