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Submissions from 2016

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Peering Below the Diffraction Limit: Robust and Specific Sorting of Viruses with Flow Cytometry, Shea T. Lance, David J. Sukovich, Kenneth M. Stedman, and Adam R. Abate

Life on the Edge—the Biology of Organisms Inhabiting Extreme Environments: An Introduction to the Symposium, Annie R. Lindgren, Bradley A. Buckley, Sarah M. Eppley, Anna-Louise Reysenbach, Kenneth M. Stedman, and Josiah T. Wagner

Rapid Purging of Genetic Load in a Metapopulation and Consequences for Range Expansion in an Invasive Plant, Gina L. Marchini, Nena Cole Sherlock, Alisa P. Ramakrishnan, David M. Rosenthal, and Mitchell B. Cruzan

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Reproducibility and Rigor In REE's Portfolio of Research, Mark McLellan, Patsy Brannon, Adriana Campa, Steven Daley-Laursen, Govind Kannan, Neil Olson, Robert Taylor, and Dawn Thilmany

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B-17 Flying Fortress Pilot’s Words for Today’s Graduates ---, Mark R. McLellan

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Cho Endonuclease Functions During DNA Interstrand Crosslink Repair in Escherichia coli, Anthonige Vidya Perera, James Brian Mendenhall, Charmain T. Courcelle, and Justin Courcelle

Hypoxia and Anoxia Tolerance in the Annual Killifish Austrofundulus Limnaeus, Jason E. Podrabsky and Natalie E. Wilson

Frequency of Extra-Pair Paternity in Scissor-Tailed Flycatchers (Tyrannus forficatus) and Other Suboscines: Are Oscines and Suboscines Different?, Diane V. Roeder, Michael S. Husak, and Michael T. Murphy

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Paternal Mitochondrial Transmission in Intra-Species Caenorhabditis briggsae Hybrids, Joseph A. Ross, Dana K. Howe, Anna Luella Coleman-Hulbert, Dee R. Denver, and Suzanne Estes

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How to Assess Your CURE: A Practical Guide for Instructors of Course-Based Undergraduate Research Experiences, Erin Shortlidge and Sara Brownell

Faculty Perspectives on Developing and Teaching Course-Based Undergraduate Research Experiences, Erin E. Shortlidge, Gita Bangera, and Sara Brownell

Moss Antheridia Are Desiccation Tolerant: Rehydration Dynamics Influence Sperm Release in Bryum Argenteum, Lloyd R. Stark, D. Nicholas McLetchie, Joshua L. Greenwood, and Sarah M. Eppley

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Mitochondrial DNA Sequence and Lack of Response to Anoxia in the Annual Killifish Austrofundulus limnaeus, Josiah T. Wagner, Florisela H. Chavez, and Jason E. Podrabsky

A Phage Display-Selected Peptide Inhibitor o fAgrobacterium Vitis Polygalacturonase, Jeremy G. Warren, George W. Kasun, Takara Leonard, and Bruce C. Kirkpatrick

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The Intervening Sequence of Coxiella burnetii: Characterization and Evolution, Indu Warrier, Mathias C. Walter, Dimitrios Frangoulidis, Rahul Raghavan, Linda D. Hicks, and Michael F. Minnick

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Paths of Heritable Mitochondrial DNA Mutation and Heteroplasmy in Reference and Gas-1 Strains of Caenorhabditis Elegans, Riana I. Wernick, Suzanne Estes, Dana K. Howe, and Dee R. Denver

Biological Rhythms: Melatonin Shapes the Space-Time Continuum of Social Communication, Walter Wilczynski and Deborah I. Lutterschmidt

Common Mycelial Networks Impact Competition in an Invasive Grass, Rachael Workman and Mitchell Cruzan

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Genomics-Informed Isolation and Characterization of a Symbiotic Nanoarchaeota System from a Terrestrial Geothermal Environment, Louie Wurch, Richard J. Giannone, Bernard S. Belisle, Carolyn Swift, Sagar Utturkar, Robert L. Hettich, Anna-Louise Reysenbach, and Mircea Podar

Submissions from 2015

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Mission Possible: How FDA Can Move at the Speed of Science, Margaret Anderson, Gail H. Cassell, Maria C. Freire, Lynn Goldman, Peter K. Honig, Frederick Kushner, Mark McLellan, Barbara J. McNeil, Martin A. Philbert, Bruce M. Psaty, Alan J. Russell, and Ellen Sigal

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RecBCD is required to Complete Chromosomal Replication: Implications for Double- Strand Break Frequencies and Repair Mechanisms, Justin Courcelle, Brian M. Wendel, Dena D. Livingstone, and Charmain T. Courcelle

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Saccular Transcriptome Profiles of the Seasonal Breeding Plainfin Midshipman Fish (Porichthys notatus), a Teleost with Divergent Sexual Phenotypes, Joshua J. Faber-Hammond, Manoj P. Samanta, Elizabeth A. Whitchurch, Dustin Manning, Joseph A. Sisneros, and Allison B. Coffin

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Isolation of Diverse Members of the Aquificales from Geothermal Springs in Tengchong, China, Brian P. Hedlund, Anna-Louise Reysenbach, Liuquin Huang, John C. Ong, Zizhang Liu, Jeremy A. Dodsworth, Reham Ahmed, Amanda J. Williams, Brandon R. Briggs, Yitai Liu, Weiguo Hou, and Hailiang Dong

Metabolism at the Max: How Vertebrate Organisms Respond to Physical Activity, Michael S. Hedrick, Thomas V. Hancock, and Stanley S. Hillman

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Increased Harbor Porpoise Mortality in the Pacific Northwest, USA: Understanding When Higher Levels May be Normal, Jessica L. Higgins, Stephen A. Raverty, Stephanie A. Norman, John Calambokidis, Joseph K. Gaydos, Deborah A. Duffield, Dyanna M. Lambourn, James M. Rice, Brad Hanson, Kristin Wilkinson, Steven J. Jeffries, Brent Norberg, and Lynne Barre

Desert Environments, Stanley D. Hillyard, Jason E. Podrabsky, and Frank van Breukelen

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Free Mate Choice Enhances Conservation Breeding in the Endangered Giant Panda, Meghan S. Martin-Wintle, David J. Shepherdson, Guiquan Zhang, Hemin Zhang, Desheng Li, Xiaoping Zhou, Rengui Li, and Ronald R. Swaisgood

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Rapid and Repeatable Shifts in Life-History Timing of Rhagoletis pomonella (Diptera: Tephritidae) Following Colonization of Novel Host Plants in the Pacific Northwestern United States, Monte Mattsson, Glen R. Hood, Jeffery L. Feder, and Luis A. Ruedas

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Coxiella burnetii and Leishmania Mexicana Residing Within Similar Parasitophorous Vacuoles Elicit Disparate Host Responses, Jess A. Millar, Raquel Valdés, Fenil Kacharia, Scott M. Landfear, Eric D. Cambronne, Rahul Raghavan, Lynn Soong, and Emilio Luis Malchiodi

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Selfish Mitochondrial DNA Proliferates and Diversifies in Small, but not Large, Experimental Populations of Caenorhabditis briggsae, Wendy S. Phillips, Anna Luella Coleman-Hulbert, Emily S. Weiss, Dana K. Howe, Sita Ping, Riana I. Wernick, Suzanne Estes, and Dee R. Denver

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Physiological Strategies During Animal Diapause: Lessons from Brine Shrimp and Annual Killifish., Jason E. Podrabsky and Steven C. Hand

Tolerance of Environmental Stress, Jason E. Podrabsky, Claire L. Riggs, and Josiah Tad Wagner

Alternate Developmental Pathways, Jason E. Podrabsky, Amie L. Romney, and Kristin M. Culpepper

Temporary Environments, Matej Polacik and Jason E. Podrabsky

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Reducing the Negative Human-Health Impacts of Bioenergy Crop Emissions through Region-Specific Crop Selection, William Christian Porter, Todd N. Rosenstiel, Alex Guenther, Jean-Francois Lamarque, and Kelley Barsanti

Ultrasonic Bone Assessment in Tursiops Truncatus: A Proposed Means for Monitoring Marine Ecosystem Health, James Powell, Gangming Luo, and Jonathan J. Kaufman

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Genome Rearrangements Can Make and Break Small RNA Genes, Rahul Raghavan, Fenil R. Kacharia, Jess A. Millar, Christine Demko Sislak, and Howard Ochman

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Effects of Sex and Mycorrhizal Fungi on Gas Exchange in the Dioecious Salt Marsh Grass Distichlis Spicata, Kassandra Reuss-Schmidt, Todd N. Rosenstiel, Sally R. Rogers, Allie G. Simpson, and Sarah M. Eppley

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Moss in the Classroom: A Tiny but Mighty Tool for Teaching Biology, Erin E. Shortlidge and James R. Hashimoto

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A Coxiella-Like Endosymbiont Is a Potential Vitamin Source for the Lone Star Tick, Todd A. Smith, Timothy Driscoll, Joseph J. Gillespie, and Rahul Raghavan

Extreme Tolerance and Developmental Buffering of UV-C Induced DNA Damage in Embryos of the Annual Killifish Austrofundulus Limnaeus, Josiah Tad Wagner and Jason E. Podrabsky

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Gene Expression Patterns That Support Novel Developmental Stress Buffering in Embryos of the Annual Killifish Austrofundulus limnaeus, Josiah T. Wagner and Jason E. Podrabsky

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Degradation by Cullin 3 and Effect on WNK Kinases Suggest a Role of KLHL2 in the Pathogenesis of Familial Hyperkalemic Hypertension, Chong Zhang, Nicholas P. Meermeier, Andrew Terker, Katharina I. Blankenstein, Jeffrey D. Singer, Juliette Hadchouel, David Ellison, and Chao-Ling Yang

Submissions from 2014

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Experimental Analysis of Nest-Site Choice and its Relationship to Nest Success in an Open-Cup–Nesting Passerine, Sarah Cancellieri and Michael T. Murphy

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Novel Computational Approaches Characterizing Knee Physiotherapy, Wangdo Kim, Antonio P. Veloso, Duarte Araújo, and Sean S. Kohles

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Report on the Workshop for Life Detection in Samples from Mars, Gerhard Kminek, Catherine Conley, Carlton C. Allen, Douglas H. Bartlett, David W. Beaty, Liane G. Benning, Rohit Bhatia, Penelope J. Boston, Caroline Duchaine, Jack D. Farmer, George J. Flynn, Daniel P. Glavin, Yuri Gorby, John E. Hallsworth, Rakesh Mogul, Duane Moser, P. Buford Price, Ruediger Pukall, David Fernandez-Remolar, Caroline L. Smith, Kenneth M. Stedman, Andrew Steele, Ramunas Stepanauskas, Henry Sun, Jorge L. Vago, Mary A. Voytek, Paul S. Weiss, and Frances Westfall

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Biomechanical Analysis of Concealed Pack Load Influences on Terrorist Gait Signatures Derived from Gröbner Basis Theory, Sean S. Kohles, Anum Barki, Kimberly D. Kendricks, and Ronald F. Tuttle

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The Influence of Vitamin D Metabolism on Gene Expression, Matrix Production and Mineralization During Osteoprecursor Cell-Based Bone Development, Shelley S. Mason, Sean S. Kohles, Shelley R. Winn, and Randy D. Zelick

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Report and Recommendations of the Balance of Crop Research Working Group of the National Agricultural Research, Extension, Education and Economics (NAREEE) Advisory Board, Mark McLellan, Leo Holt, Twilya L'Ecuyer, Robert Taylor, Julia Sabin, Milo Shult, Anne Marie Thro, and Paul Heisey

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Antibacterial Gene Transfer Across the Tree of Life, Jason A. Metcalf, Lisa J. Funkhouser-Jones, Kristen A. Brileya, Anna-Louise Reysenbach, and Seth R. Bordenstein

Water Cooling Method to Improve the Performance of Field-Mounted, Insulated, and Concentrating Photovoltaic Modules, Matthew K. Smith, Hanny Selbak, Carl C. Wamser, Nicholas U. Day, Matthew Krieske, David J. Sailor, and Todd Rosenstiel

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Endogenous ROS Levels in C. Elegans Under Exogenous Stress Support Revision of Oxidative Stress Theory of Life-History Tradeoffs, Samson W. Smith, Leigh C. Latta IV, Dee R. Denver, and Suzanne Estes

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Using Phylogenetically-Informed Annotation (PIA) to search for light-interacting Genes in Transcriptomes from Non-Model Organisms, Daniel L. Speiser, Molly S. Pankey, Alexander K. Zaharoff, Barbara A. Battelle, Heather D. Bracken-Grissom, Jesse W. Breinholt, Seth M. Bybee, Thomas W. Cronin, Anders Garm, Annie R. Lindgren, Nipam H. Patel, Megan L. Porter, Meredith E. Protas, Ajna S. Rivera, Jeanne M. Serb, Kirk S. Zigler, Keith A. Crandall, and Todd H. Oakley

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Structural Insights into the Architecture of the Hyperthermophilic Fusellovirus SSV1, Kenneth M. Stedman, Melissa DeYoung, Mitul Saha, Michael B. Sherman, and Marc C. Morais

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Variation in Sex Allocation and Floral Morphology in an Expanding Distylous Plant Hybrid Complex, Jennifer Rhode Ward, M. Leigh Cowart, Julie Clifford, Mieko Camp, and Mitchell B. Cruzan

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Identification of Novel Small RNAs and Characterization of the 6S RNA of Coxiella burnetii, Indu Warrier, Linda D. Hicks, James M. Battisti, Rahul Raghavan, and Michael F. Minnick

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Novel Cul3 Binding Proteins Function to Remodel E3 Ligase Complexes, Wananit Wimuttisuk, Mark West, Brittney Davidge, Kebing Yu, Arthur Salomon, and Jeffrey D. Singer

Submissions from 2013

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Distance and Sex Determine Host Plant Choice by Herbivorous Beetles, Daniel J. Ballhorn, Stefanie Kautz, and Martin Heil

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Effect of Mycorrhizal Colonization and Light Limitation on Growth and Reproduction of Lima Bean (Phaseolus lunatus L.), Daniel J. Ballhorn and Jess A. Millar

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Taxis Toward Hydrogen Gas by Methanococcus Maripaludis, Kristen A. Brileya, James M. Connolly, Carey Downey, Robin Gerlach, and Matthew W. Fields

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Can Long-Range PCR Be Used to Amplify Genetically Divergent Mitochondrial Genomes for Comparative Phylogenetics? A Case Study within Spiders (Arthropoda: Araneae), Andrew G. Briscoe, Sara Goodacre, Susan E. Masta, Martin I. Taylor, Miquel A. Arnedo, David Penny, John Kenny, and Simon Creer

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Rapid Change in Shallow Water Fish Species Composition in an Historically Stable Antarctic Environment, Bradley A. Buckley

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Field Evaluation of Arbuscular Mycorrhizal Fungal Colonization in Bacillus thuringiensis Toxin-Expressing (Bt) and Non-Bt Maize, Tanya E. Cheeke, Mitchell B. Cruzan, and Todd N. Rosenstiel

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Cross-Species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma, Eleanor Y. Chen, Kimberly P. Dobrinski, Kim H. Brown, Ryan Clagg, Elena Edelman, Myron S. Ignatius, Jin Yun Helen Chen, Jillian Brockmann, G. Petur Nielsen, Sridhar Ramaswamy, Charles Keller, Charles Lee, and David M. Langenau

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Sequencing and De Novo Transcriptome Assembly of Brachypodium sylvaticum (Poaceae), Samuel E. Fox, Justin Preece, Jeffrey A. Kimbrel, Gina L. Marchini, Abigail Sage, Ken Youens-Clark, Mitchell B. Cruzan, and Pankaj Jaiswal

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Migration Timing and Wintering Areas of Three Species of Flycatchers (Tyrannus) Breeding in the Great Plains of North America, Alex E. Jahn, Victor R. Cueto, James W. Fox, Michael S. Husak, Daniel H. Kim, Diane V. Landoll, Jesús Pinto Ledezma, Heather K. LePage, Douglas J. Levey, Michael T. Murphy, and Rosalind B. Renfrew

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Evolution of a Higher Intracellular Oxidizing Environment in Caenorhabditis elegans under Relaxed Selection, Joanna Joyner-Matos, Kiley A. Hicks, Dustin Cousins, Michelle Keller, Dee R. Denver, Charles F. Baer, and Suzanne Estes

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Reversible Inactivation and Desiccation Tolerance of Silicified Viruses, James R. Laidler, Jessica A. Shugart, Sherry L. Cady, Keith S. Bahjat, and Kenneth M. Stedman

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Extrahepatic 25-Hydroxylation of Vitamin D3 in an Engineered Osteoblast Precursor Cell Line Exploring the Influence on Cellular Proliferation and Matrix Maturation during Bone Development, Shelley S. Mason, Sean S. Kohles, Shelley R. Winn, and Randy D. Zelick

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Avoidance of Apoptosis in Embryonic Cells of the Annual Killifish Austrofundulus limnaeus Exposed to Anoxia, Camie Lynn Meller and Jason E. Podrabsky

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Insights into Archaeal Evolution and Symbiosis from the Genomes of a Nanoarchaeon and its Inferred Crenarchaeal Host from Obsidian Pool, Yellowstone National Park, Mircea Podar, Kira S. Makarova, David E. Graham, Yuri L. Wolf, Eugene V. Koonin, and Anna-Louise Reysenbach

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Mesoaciditoga lauensis gen. nov., sp. nov., a moderate thermoacidophilic Thermotogales from a deep-sea hydrothermal vent, Anna-Louise Reysenbach, Yitai Liu, Annie R. Lindgren, Issac D. Wagner, Christine Demko Sislak, Anchelique Mets, and Stefan Schouten

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Residential Edges as Ecological Traps: Postfledgling Survival of a Ground-Nesting Passerine in a Forested Urban Park, Amy A. Shipley, Michael T. Murphy, and Adam H. Elzinga

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Microbial Biogeochemistry of Boiling Springs Lake: a Physically Dynamic, Oligotrophic, Low-p H Geothermal Ecosystem, Patricia Lynne Siering, Gordon V. Wolfe, Mark S. Wilson, A. N. Yip, Cynthia M. Carey, Colin D. Wardman, Russell Scott Shapiro, Kenneth M. Stedman, Jennifer E. Kyle, Tong Yuan, Joy D. Van Nostrand, Zhili He, and Jizhong Zhou

Effects of Natural and Manual Cleaning on Photovoltaic Output, Matthew K. Smith, Carl C. Wamser, Keith E. James, Seth Sinclair Moody, David J. Sailor, and Todd Rosenstiel

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Consequences of Mycorrhizal Colonization for Piriqueta Morphotypes under Drought Stress, Paul Sochacki, Jennifer Rhode Ward, and Mitchell B. Cruzan

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Metagenome Sequence Analysis of Filamentous Microbial Communities Obtained from Geochemically Distinct Geothermal Channels Reveals Specialization of Three Aquificales Lineages, Cristina Takacs-Vesbach, William P. Inskeep, Zackary J. Jay, Markus J. Herrgard, Douglas B. Rusch, Susannah G. Tringe, Mark A. Kozubal, Natsuko Hamamura, Richard E. Macur, Bruce W. Fouke, Anna-Louise Reysenbach, Timothy R. McDermott, Ryan deM. Jennings, Nicolas W. Hengartner, and Gary Xie

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Asian Primate Species Richness Correlates with Rainfall, Yi-Chen Wang, Amrita Srivathsan, Chen-Chieh Feng, Agus Salim, and Myron Shekelle

Submissions from 2012

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Cephalopod Genomics: A Plan of Strategies and Organization, Caroline B. Albertin, Laure Bonnaud, C. Titus Brown, Wendy J. Crookes-Goodson, Rute R. da Fonseca, Carlo Di Cristo, Brian P. Dilkes, Eric Edsinger-Gonzales, Robert M. Freeman Jr., Roger T. Hanlon, Kristen M. Koenig, Annie R. Lindgren, Mark Q. Martindale, Patrick Minx, Leonid L. Moroz, Marie-Therese Nödl, Spencer V. Nyholm, Atsushi Ogura, Judit R. Pungor, Joshua J. C. Rosenthal, Erich M. Schwarz, Shuichi Shigeno, Jan M. Strugnell, Tim Wollesen, Guojie Zhang, and Clifton W. Ragsdale

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Differential Virus Host-Ranges of the Fuselloviridae of Hyperthermophilic Archaea: Implications for Evolution in Extreme Environments, Ruben M. Ceballos, Caleb D. Marceau, Joshua O. Marceau, Steven Morris, Adam J. Clore, and Kenneth M. Stedman

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Evidence of reduced arbuscular mycorrhizal fungal colonization in multiple lines of Bt maize, Tanya E. Cheeke, Todd N. Rosenstiel, and Mitchell B. Cruzan

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Selfish Little Circles: Transmission Bias and Evolution of Large Deletion-Bearing Mitochondrial DNA in Caenorhabditis briggsae Nematodes, Katie A. Clark, Dana K. Howe, Kristin Gafner, Danika Kusuma, Sita Ping, and Suzanne Estes

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The Breeding Biology of the Northern Pygmy Owl: Do the Smallest of the Small Have an Advantage?, John F. Deshler and Michael T. Murphy

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Sub-Antarctic and High Antarctic Notothenioid Fishes: Ecology and Adaptational Biology Revealed by the ICEFISH 2004 Cruise of RVIB Nathaniel B. Palmer, H. William Detrich III, Bradley A. Buckley, Daniel F. Doolittle, Christopher D. Jones, and Susanne J. Lockhart

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A Novel Virus Genome Discovered in an Extreme Environment Suggests Recombination Between Unrelated Groups of RNA and DNA Viruses, Geoffrey S. Diemer and Kenneth M. Stedman

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Distribution, abundance, and diversity patterns of the thermoacidophilic “deep-sea hydrothermal vent euryarchaeota 2”, Gilberto Flores, Issac D. Wagner, Yitai Liu, and Anna-Louise Reysenbach

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Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies, J. Kimble Frazer, Lance A. Batchelor, Diana F. Bradley, Kim H. Brown, Kimberly P. Dobrinski, Charles Lee, and Nikolaus S. Trede

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In Vivo Quantification Reveals Extensive Natural Variation in Mitochondrial Form and Function in Caenorhabditis briggsae, Kiley Ann Hicks, Dana K. Howe, Aubrey Leung, Dee R. Denver, and Suzanne Estes

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A Genetic Study of SSV1, the Prototypical Fusellovirus, Eric Iverson and Kenneth M. Stedman

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Inefficient Replication Reduces RecA-mediated Repair of UVdamaged Plasmids introduced into competent Escherichia coli, Harout Arthur Jeiranian, Charmain T. Courcelle, and Justin Courcelle

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Host Plant Use by Competing Acacia-Ants: Mutualists Monopolize While Parasites Share Hosts, Stefanie Kautz, Daniel J. Ballhorn, Johannes Kroiss, Steffen U. Pauls, Corrie S. Moreau, Sascha Eilmus, Erhard Strohm, and Martin Heil

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Cytoskeletal Strains in Modeled Optohydrodynamically Stressed Healthy and Diseased Biological Cells, Sean S. Kohles, Yu Liang, and Asit K. Saha

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A multi-gene phylogeny of Cephalopoda supports convergent morphological evolution in association with multiple habitat shifts in the marine environment, Annie R. Lindgren, Molly S. Pankey, Frederick G. Hochberg, and Todd H. Oakley

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Cell Cycle Arrest Associated with Anoxia-Induced Quiescence, Anoxic Preconditioning, and Embryonic Diapause in Embryos of the Annual Killifish Austrofundulus Limnaeus, Camie Lynn Meller, Robert Meller, Roger P. Simon, Kristin M. Culpepper, and Jason E. Podrabsky

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UvrD Participation in Nucleotide Excision Repair Is Required for the Recovery of DNA Synthesis following UV-Induced Damage in Escherichia coli, Kelley Nicole Newton, Charmain T. Courcelle, and Justin Courcelle

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Phylotranscriptomics to Bring the Understudied into the Fold: Monophyletic Ostracoda, Fossil Placement, and Pancrustacean Phylogeny, Todd H. Oakley, Joanna M. Wolfe, Annie R. Lindgren, and Alexander K. Zaharoff

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Pseudoscorpion mitochondria show rearranged genes and genome-wide reductions of RNA gene sizes and inferred structures, yet typical nucleotide composition bias, Sergey Ovchinnikov and Susan E. Masta

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Anoxia Tolerance During Vertebrate Development - Insights from Studies on the Annual Killifish Austrofundulus limnaeus, Jason E. Podrabsky, Claire L. Riggs, and Jeffrey M. Duerr

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Spatio-Temporal Differentiation and Sociality in Spiders, Jessica Purcell, João Vasconcellos-Neto, Jeffrey Alan Fletcher, Marcelo O. Gonzaga, and Leticia Avilés

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A Selective Force Favoring Increased G+C Content in Bacterial Genes, Rahul Raghavan, Yogeshwar D. Kelkar, and Howard Ochman